Golgi apparatus and acid phosphatase in mammary gland and kidney cells under the influence of diethylstilbestrol (DES).

Folia histochemica et cytochemica Pub Date : 1982-01-01
S M El-Fiky, A I Michael, A Abdel Azim, I Youssif, M Youssif
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Abstract

It is commonly accepted that hormonal disturbances in experimental animals produce pathological changes in several organs namely in mammary glands and kidney. Taking into consideration the close relationship between acid phosphatase and Golgi apparatus, the present study was undertaken, to study the relationship in kidney and mammary gland cells under the influence of DES. The observation indicate, that acid phosphatase and Golgi apparatus were localized in the cytoplasm of mammary gland and kidney cells. It has also been found a parallel change in the activity of acid phosphatase and the degree of development of Golgi apparatus after DES administration.

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己烯雌酚(DES)对乳腺和肾细胞高尔基体和酸性磷酸酶的影响。
人们普遍认为,实验动物的激素紊乱会引起乳腺和肾脏等几个器官的病理改变。考虑到酸性磷酸酶与高尔基体的密切关系,本研究在DES的影响下,研究了肾脏和乳腺细胞中酸性磷酸酶和高尔基体的关系。观察发现,酸性磷酸酶和高尔基体定位于乳腺和肾脏细胞的细胞质中。经DES处理后,酸性磷酸酶的活性和高尔基体的发育程度也发生了平行变化。
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