Effect of steroid prophylaxis and of elective caesarean section on maternal and fetal cortisol values.

I Veszelovszky, Z B Nagy, G Falkay, I Morvay, L Kovalovszky, M Molnár, L Bódis
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Abstract

The cortisol level was studied during and after delivery in the mothers and their newborns after normal deliveries, elective Caesarean sections, and steroid pre-treated vaginal deliveries. The suppressive effect of Caesarean section, and steroid pre-treated vaginal deliveries. The suppressive effect of exogenous steroid was observed in both the mother and the newborn but its extent was not significant and its duration transitory; in 48 hours it disappeared. In the newborns delivered by elective Caesarean section, an extreme increase in the cortisol level was observed. The cortisol level in the amniotic fluid was not suitable for evaluating the function of the hypophysis-adrenal axis, especially not after steroid prophylaxis.

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类固醇预防和择期剖宫产对母胎皮质醇值的影响。
在正常分娩、选择性剖腹产和经类固醇预处理的阴道分娩中,研究了分娩期间和分娩后母亲及其新生儿的皮质醇水平。剖宫产和经类固醇预处理的阴道分娩的抑制作用。外源性类固醇对母鼠和新生儿均有抑制作用,但作用程度不显著,持续时间短暂;48小时后就消失了。在选择性剖腹产分娩的新生儿中,观察到皮质醇水平的极端增加。羊水皮质醇水平不适合评价垂体-肾上腺轴的功能,尤其是类固醇预防后。
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