{"title":"Absorption of isosorbide dinitrate by PVC infusion bags and administration sets.","authors":"M G Lee, V Fenton-May","doi":"10.1111/j.1365-2710.1981.tb00995.x","DOIUrl":null,"url":null,"abstract":"<p><p>Isosorbide dinitrate is shown to be absorbed onto PVC bags and administration sets, resulting in a fall in potency to about 70-80% of its initial value in the first 15-30 min of an i.v. infusion. The drug was not absorbed by glass or polypropylene.</p>","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"6 3","pages":"209-11"},"PeriodicalIF":0.0000,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-2710.1981.tb00995.x","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical and hospital pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/j.1365-2710.1981.tb00995.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
Isosorbide dinitrate is shown to be absorbed onto PVC bags and administration sets, resulting in a fall in potency to about 70-80% of its initial value in the first 15-30 min of an i.v. infusion. The drug was not absorbed by glass or polypropylene.