A successful kinetic approach to the screening of preservation efficacy of benzylalcohol--a neutral-type preservative--is described. The D-value, activation energy (Ea), temperature coefficient (Q10) and concentration exponent (n) were used as parameters in determining the influence of different factors on the efficacy of benzylalcohol. Factors, such as the pH of the solution, temperature and concentration of the preservative were investigated. The study was carried out using five micro-organisms: Aspergillus niger, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus.
{"title":"Studies on the evaluation of preservative efficacy--II. The determination of antimicrobial characteristics of benzylalcohol.","authors":"M S Karabit, O T Juneskans, P Lundgren","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A successful kinetic approach to the screening of preservation efficacy of benzylalcohol--a neutral-type preservative--is described. The D-value, activation energy (Ea), temperature coefficient (Q10) and concentration exponent (n) were used as parameters in determining the influence of different factors on the efficacy of benzylalcohol. Factors, such as the pH of the solution, temperature and concentration of the preservative were investigated. The study was carried out using five micro-organisms: Aspergillus niger, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus.</p>","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"11 4","pages":"281-9"},"PeriodicalIF":0.0,"publicationDate":"1986-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14653868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic progress--review XVIII. Cystic fibrosis.","authors":"J A Kohler, C J Rolles","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"11 1","pages":"21-32"},"PeriodicalIF":0.0,"publicationDate":"1986-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14636429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A review of the treatment of migraine.","authors":"S Nightingale","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"9 4","pages":"271-82"},"PeriodicalIF":0.0,"publicationDate":"1984-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17456687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in the treatment of poisoning I.","authors":"D A Boldy, B M Buckley, J A Vale","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"9 3","pages":"147-60"},"PeriodicalIF":0.0,"publicationDate":"1984-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17446791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stability and blanching potential of corticosteroid ointments.","authors":"Kirsch, J R Gibson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"9 2","pages":"143"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17298445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic progress--review XII. Treatment of multiple myeloma.","authors":"J E Oakley, I M Franklin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"9 1","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"1984-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17431757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic progress--review XI. Drugs in asthma.","authors":"I D Green","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"9 1","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"1984-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17210093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beta blockade in the management of thyrotoxicosis.","authors":"R Wilkinson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"8 4","pages":"323-32"},"PeriodicalIF":0.0,"publicationDate":"1983-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17206399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medical treatment of ulcerative colitis and Crohn's disease.","authors":"J M Rhodes","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"8 3","pages":"219-32"},"PeriodicalIF":0.0,"publicationDate":"1983-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17205137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1983-06-01DOI: 10.1111/j.1365-2710.1983.tb01039.x
S R Smith, G Blackledge
The frequency of occurrence of rumours at different sites varies widely, but cancer of the lung, alimentary tract and breast account for at least 50% of all malignancy. The incidence rates of a number of types of tumour for males and females are shown in Table 2, together with the proportion that each represents of all cancer and the median age at presentation. An important characteristic of malignant tumours is the capacity for dissemination of tumour cells throughout the host. Such metastatic spread occurs early in the natural history of a large proportion of tumours, frequently before the primary lesion is clinically detectable. It is clear therefore, that in such cases treatment directed towards the primary tunour alone, such as surgical removal, cannot possibly achieve control of the disease. Some form of systemic therapy is necessary and this provides part of the rationale for the use of cytotoxic drugs, given orally or parenterally, which interfere with some facet of
{"title":"Therapeutic progress--review VIII. Do the newer cytotoxic drugs represent a significant advance in the treatment of cancer?","authors":"S R Smith, G Blackledge","doi":"10.1111/j.1365-2710.1983.tb01039.x","DOIUrl":"https://doi.org/10.1111/j.1365-2710.1983.tb01039.x","url":null,"abstract":"The frequency of occurrence of rumours at different sites varies widely, but cancer of the lung, alimentary tract and breast account for at least 50% of all malignancy. The incidence rates of a number of types of tumour for males and females are shown in Table 2, together with the proportion that each represents of all cancer and the median age at presentation. An important characteristic of malignant tumours is the capacity for dissemination of tumour cells throughout the host. Such metastatic spread occurs early in the natural history of a large proportion of tumours, frequently before the primary lesion is clinically detectable. It is clear therefore, that in such cases treatment directed towards the primary tunour alone, such as surgical removal, cannot possibly achieve control of the disease. Some form of systemic therapy is necessary and this provides part of the rationale for the use of cytotoxic drugs, given orally or parenterally, which interfere with some facet of","PeriodicalId":77862,"journal":{"name":"Journal of clinical and hospital pharmacy","volume":"8 2","pages":"103-13"},"PeriodicalIF":0.0,"publicationDate":"1983-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-2710.1983.tb01039.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17407857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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