A rat model of the fetal alcohol syndrome--preliminary histological findings.

Currents in alcoholism Pub Date : 1981-01-01
B T Sherwin, S Jacobson, D Zagorski
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Abstract

A semipurified liquid diet was used to develop a chronic rat model of fetal alcohol syndrome. Adult female rats were fed a control or 40% ethanol (percent of total caloric intake) liquid diet. Additional controls were pair fed to the 40% experimental group. Results of the effects of these diets on the offspring included both qualitative and quantitative changes observed in Golgi study of hippocampal pyramidal neurons.

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胎儿酒精综合征大鼠模型——初步组织学发现。
采用半纯化液体饲料建立慢性胎儿酒精综合征大鼠模型。成年雌性大鼠被喂食对照或40%乙醇(总热量摄入的百分比)的液体饮食。在40%的实验组中添加对照组。这些饮食对后代的影响结果包括在高尔基体研究中观察到的海马锥体神经元的定性和定量变化。
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