[Gastric acid response to food in duodenal ulcer patients before and after selective proximal vagotomy (SPV) (author's transl)].

Abstract

In duodenal ulcer patients the maximal acid secretion induced by pentagastrin is significantly higher than the meal-induced acid secretion (10% peptone, pH 5.5). Three months after SPV there is no difference in pentagastrin and meal-induced stimulation. There is a reduction of 56% in insulin-negative patients after SPV, but only of 9% in insulin-positive patients. Basal serum gastrin levels increased significantly after SPV, but there is no difference in postprandial serum gastrin levels and in insulin-positive and insulin-negative patients. Intragastric titration seems to be a subtle method for testing the completeness of SPV.