[Hypoxia of tissue peripheral shunting in massive transfusion of erythrocytes and whole donor blood].

Abstract

In response to correction of lethal and sublethal blood loss with excessive quantities of donor blood two types of cardiovascular adverse reactions may occur immediately after transfusion: either increased or decreased minute blood volume. This conclusion was made after 65 dog experiments on hemodynamics and blood gases. Though the absolute value of cardiac output changes differently in both cases there are signs of oxygen insufficiency.