Drugs from the peptide venoms of marine cone shells.

Australasian biotechnology Pub Date : 1994-09-01
R J Lewis, J P Bingham, A Jones, P F Alewood, P R Andrews
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Abstract

Australian cone shell venoms are being investigated as an exciting new source of bioactive peptides as part of a new collaborative project between the 3D Centre and AMRAD. Initial studies have already revealed a number of new and novel acting peptides amongst the hundred or so small, heavily constrained peptides present in the venom of each cone shell. The aim of the project is to develop peptidomimetic drugs based on a selection of these native peptides.

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从海洋锥壳的肽毒液中提取药物。
作为3D中心和AMRAD之间的新合作项目的一部分,澳大利亚锥壳毒液正在作为一种令人兴奋的生物活性肽的新来源进行研究。最初的研究已经揭示了一些新的和新颖的作用肽在100个左右的小,严重限制肽存在于每个锥体壳的毒液。该项目的目的是基于这些天然肽的选择开发拟肽药物。
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