[A systematic genetic-epidemiologic family study of patients with Alzheimer disease--experience with the MIRAGE study in Germany].

Zeitschrift fur Gerontologie Pub Date : 1994-09-01
N Lautenschlager, E J Foley, M Haupt, R Zimmer, L A Farrer, A Kurz
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Abstract

A register of the families of 60 patients with Alzheimer's disease was established with two questionnaires (the Family History Questionnaire and the Patient History Questionnaire). These questionnaires, instruments of the MIRAGE study, were translated into German. 35% of the families had more than one family member affected with dementia. The frequencies of the risk factors that were studied were surprisingly high. The responses of the family members to the study were very positive and encourage further investigation in the field of genetic epidemiology in Alzheimer's disease.

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[阿尔茨海默病患者的系统遗传流行病学家庭研究——德国MIRAGE研究的经验]。
通过两份问卷(家族史问卷和患者病史问卷)对60名阿尔茨海默病患者的家庭进行了登记。这些问卷,MIRAGE研究的工具,被翻译成德语。35%的家庭有一个以上的家庭成员患有痴呆症。被研究的风险因素的频率高得惊人。家庭成员对这项研究的反应非常积极,并鼓励在阿尔茨海默病遗传流行病学领域进行进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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