Orosomucoid and haptoglobin polymorphisms in two Spanish Pyrenean populations.

T Sandiumenge, S Vives, P Moral
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Abstract

Serum samples of autochthonous individuals from the Garrotxa prepyrenean region, and the Pallars Sobirà valley were screened for HP (Haptoglobin) and ORM (Orosomucoid) types by polyacrylamide isoelectric focusing and electrophoresis. The allele frequencies estimated were HP*1 = 0.3902 and ORM1*S = 0.3697 for Pallars Sobirà, and HP*1 = 0.4161 and ORMS1*S = 0.3691 in the Garrotxa. While our results for the HP system are within the range of variation of the Iberian Peninsula, the ORM1 protein shows a remarkable degree of variation among these populations.

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两个西班牙比利牛斯山脉人群的类珠状体和触珠蛋白多态性。
采用聚丙烯酰胺等电聚焦和电泳技术对Garrotxa preyrenean地区和Pallars sobir山谷的土著个体血清进行HP (Haptoglobin)和ORM (Orosomucoid)型筛选。等位基因频率分别为:Pallars sobircom的HP*1 = 0.3902和ORM1*S = 0.3697, Garrotxa的HP*1 = 0.4161和ORMS1*S = 0.3691。虽然我们对HP系统的研究结果在伊比利亚半岛的变异范围内,但ORM1蛋白在这些种群中表现出显著的变异程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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