Renate Lederer, Elisabeth Radeke, Cesare Mondadori
{"title":"Facilitation of social learning by treatment with an NMDA receptor antagonist","authors":"Renate Lederer, Elisabeth Radeke, Cesare Mondadori","doi":"10.1016/0163-1047(93)90409-B","DOIUrl":null,"url":null,"abstract":"<div><p>A single oral treatment with 0.3 mg/kg of the competitive NMDA receptor blocker CGP 37 849 improved the retention performance of rats in a social memory paradigm. The effect disappeared with increasing doses: at 1 mg/kg a positive trend could still be observed; at 3 mg/kg no effect whatever was detectable.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 3","pages":"Pages 220-224"},"PeriodicalIF":0.0000,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90409-B","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavioral and neural biology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/016310479390409B","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
A single oral treatment with 0.3 mg/kg of the competitive NMDA receptor blocker CGP 37 849 improved the retention performance of rats in a social memory paradigm. The effect disappeared with increasing doses: at 1 mg/kg a positive trend could still be observed; at 3 mg/kg no effect whatever was detectable.