[Screening for sleep apnea syndrome].

P Kehrer, L P Nicod
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Abstract

Sleep apnea syndrome (SAS) consists of nocturnal snoring interrupted by obstructive apnea and of diurnal symptoms like hypersomnolence as a consequence of sleep fragmentation. Cardiovascular morbidity and mortality associated with this syndrome justify early detection and appropriate treatment. Polysomnography is still a frequently used method for early detection; however, several disadvantages like duration, discomfort and expense led to a search for alternatives. Since the beginning of the eighties, oximetry allows recording of nocturnal oxygen saturation of hemoglobin even at home. Nocturnal oximetry reveals O2-desaturation associated with apnea and thus permits often to diagnose or exclude SAS. Diagnosis of SAS is made when at least 20 desaturations per hour with an amplitude of at least 4% are recorded. On the other hand, normal nocturnal oximetry nearly excludes SAS. In those cases where nocturnal oximetry is not diagnostic, polysomnography remains the method of choice. Departing from published work, a model for SAS detection, based mainly on nocturnal oximetry, is proposed.

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[筛查睡眠呼吸暂停综合症]。
睡眠呼吸暂停综合征(SAS)包括夜间打鼾被阻塞性呼吸暂停打断,以及睡眠破碎导致的嗜睡等白天症状。与该综合征相关的心血管疾病发病率和死亡率值得早期发现和适当治疗。多导睡眠图仍然是一种常用的早期检测方法;然而,持续时间、不适和费用等缺点促使人们寻找替代方案。从八十年代开始,血氧仪可以在家里记录夜间血红蛋白的氧饱和度。夜间血氧饱和度测定显示与呼吸暂停有关的o2去饱和,因此通常可以诊断或排除SAS。当记录到每小时至少20次且幅度至少为4%的去饱和时,诊断为SAS。另一方面,正常的夜间血氧测定几乎排除了SAS。在那些夜间血氧测定不能诊断的病例中,多导睡眠描记术仍然是选择的方法。从已发表的工作出发,提出了一种主要基于夜间血氧饱和度的SAS检测模型。
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