Health care delivery, zidovudine use, and survival of women and men with AIDS.

B J Turner, L E Markson, L J McKee, R Houchens, T Fanning
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Abstract

The aim of this study was to define predictors of survival for women and men after AIDS diagnosis. We examined health care delivery and drug therapy in the year before AIDS diagnosis for continuously enrolled New York State Medicaid beneficiaries with AIDS in 1988-1990. We examined the association of these factors with survival after AIDS diagnosis. Of 1,077 women and 1,871 men, 60% of both gender groups were drug users. In both risk groups, women had more outpatient visits than men but were equally likely to visit an AIDS specialist. In those who were not drug users, men were twice as likely as women to receive either zidovudine or Pneumocystis carinii pneumonia prophylaxis. No difference appeared among drug users. Survival after AIDS diagnosis was similar by gender for those who were not drug users (RR = 1.09; 95% CI = 0.90-1.33). In drug users, women had a slightly lower risk of death than men (RR = 0.84; 95% CI = 0.72-0.98). Risk of death after AIDS diagnosis was higher for persons starting zidovudine earlier in both risk groups. Among drug users, women received more ambulatory care and survived slightly longer than men. Among those who were not drug users, survival was similar by gender even after adjusting for differences in care.

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卫生保健的提供、齐多夫定的使用与艾滋病男女患者的生存。
本研究的目的是确定艾滋病诊断后女性和男性生存的预测因素。我们检查了1988-1990年连续登记的纽约州医疗补助受益人艾滋病患者在艾滋病诊断前一年的医疗服务和药物治疗。我们研究了这些因素与艾滋病诊断后生存的关系。在1,077名女性和1,871名男性中,两种性别群体中都有60%是吸毒者。在这两个风险组中,女性比男性有更多的门诊就诊,但同样有可能去看艾滋病专家。在非吸毒者中,男性接受齐多夫定或卡氏肺囊虫肺炎预防治疗的可能性是女性的两倍。吸毒者之间没有差异。非吸毒者艾滋病患者的性别生存率相似(RR = 1.09;95% ci = 0.90-1.33)。在吸毒者中,女性的死亡风险略低于男性(RR = 0.84;95% ci = 0.72-0.98)。在两个危险组中,较早开始使用齐多夫定的人在诊断出艾滋病后死亡的风险较高。在吸毒者中,女性接受了更多的门诊治疗,存活时间略长于男性。在不吸毒的人群中,即使在调整了护理差异后,性别差异的生存率也是相似的。
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