[Risk of recurrence in HELLP syndrome].

D Spitzer, H Steiner, A Graf, M Klein, A Staudach
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Abstract

The recurrence risk of HELLP-syndrome is reported to be between 2.6% and 24%. But yet, there are no accurate case reports about this topic available. In a retrospective study, 25 patients, which had suffered from a pre partum HELLP-syndrome, were interviewed about possible subsequent pregnancies. In 7 patients 8 pregnancies were found, which began between 5 and 55 months after the HELLP-syndrome. No recurrence of a HELLP-syndrome was observed in these 7 patients. Although in 71% a hypertension had been present during the HELLP-syndrome, only 1 patient had an elevated blood pressure in the subsequent pregnancy. Whilst all of the patients with HELLP-syndrome had been delivered by cesarean section, 50% of the patients were delivered vaginally in the subsequent pregnancy. There was no evidence of maternal or neonatal complications related to HELLP-syndrome. Nevertheless, even if the recurrence risk seems to be low, pregnancies after HELLP syndrome should be observed carefully.

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[HELLP综合征复发的风险]。
据报道,help综合征的复发风险在2.6%至24%之间。但是,目前还没有关于这一主题的准确病例报告。在一项回顾性研究中,对25名患有产前help -syndrome的患者进行了关于可能的后续怀孕的访谈。在7例患者中发现8例妊娠,妊娠开始于help综合征后5至55个月。7例患者无help -综合征复发。尽管71%的患者在help -综合征期间存在高血压,但只有1例患者在随后的怀孕期间血压升高。虽然所有的help综合征患者都是通过剖宫产分娩的,但50%的患者在随后的怀孕中是顺产的。没有证据表明产妇或新生儿并发症与help -综合征有关。然而,即使复发风险似乎很低,HELLP综合征后的妊娠也应仔细观察。
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[Symposium on Uterine Contraction and Beginning of Labor. Aachen, September 1993]. [Uterine contraction and labor onset. Overview]. [Control of labor onset in the human]. [Biochemical principles of cervix ripening and dilatation]. [Role of the cervix uteri at labor onset from ultrasound studies].
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