Isolation of an immunosuppressive lectin from Phaseolus vulgaris L. cv Cacahuate using stroma.

F Vargas-Albores, J Hernández, F Córdoba, E Zenteno
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引用次数: 6

Abstract

An immunosuppressive lectin was isolated from seed of Phaseolus vulgaris cv Cacahuate using physically entrapped stroma. The lectin was found to be a 94 kDa tetrameric protein. When 50 micrograms, of this lectin were administered intraperitoneally 2 days before the immunization with sheep red blood cells, humoral response against the immunogen was completely inhibited. Other properties of the protein are discussed.

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利用基质法从香菜豆中分离免疫抑制凝集素。
采用物理包埋基质法从可可酸菜豆种子中分离出一种免疫抑制凝集素。凝集素是一个94 kDa的四聚体蛋白。在绵羊红细胞免疫前2天,腹腔注射50微克这种凝集素,对免疫原的体液反应被完全抑制。讨论了该蛋白的其他性质。
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