Receptor scintigraphy with 111In-pentetreotide for endocrine gastroenteropancreatic tumors.

K Joseph, J Stapp, J Reinecke, H J Skamel, H Höffken, C Neuhaus, H Lenze, M E Trautmann, R Arnold
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Abstract

Receptor scintigraphy with 111In-pentetreotide is a simple method with a sensitivity of 86% for the localization of the primary tumor and its metastases in patients presenting with the clinical and biochemical symptoms of an endocrine tumor of the gastrointestinal tract or the pancreas. As a whole-body scintigraphic technique it covers all body regions and is also able to reveal small tumors which either cannot be detected or can only be detected with difficulty by the usual imaging methods. In 85 patients with GEP tumors or after operative removal of such tumors, receptor scintigraphy proved to be superior to ultrasound and computed tomography in 34%, equal in 52%, and inferior in 14% of the cases.

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111in -戊替肽受体显像治疗内分泌胃肠胰腺肿瘤。
111in - penteotide受体显像是一种简单的方法,对于出现胃肠道或胰腺内分泌肿瘤临床和生化症状的患者原发肿瘤及其转移灶的定位,灵敏度为86%。作为一种全身显像技术,它覆盖了身体的所有区域,也能够显示常规成像方法无法检测到或难以检测到的小肿瘤。在85例GEP肿瘤患者或手术切除后,受体显像优于超声和计算机断层扫描的比例为34%,与超声和计算机断层扫描相同的比例为52%,低于超声和计算机断层扫描的比例为14%。
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Diabetes Care and Research in Europe. 3rd European meeting for the Implementation of the St. Vincent Declaration. Athens, Greece, March 29-April 1, 1995. Abstracts. Molecular mechanisms of somatostatin's inhibition of hormone release: participation of voltage-gated calcium channels and G-proteins. Somatostatin Receptor Imaging. 1st German meeting. Stuttgart, September 1992. Biodistribution of 111In-pentetreotide and dosimetric considerations with respect to somatostatin receptor expressing tumor burden. Receptor scintigraphy with 111In-pentetreotide for endocrine gastroenteropancreatic tumors.
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