Urinary excretion of indolylacryloylglycine, indolylacetic acid and 5-hydroxyindolylacetic acid in burn patients.

E Marklová, L Klein, I M Hais
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Abstract

Indolylacryloylglycine (IAcrGly) is a regular constituent of human urine. Changes in its excretion have been observed, among other conditions, in some skin diseases. Skin lesions in burns are dealt with in the present paper. IAcrGly excretion has been followed during several weeks of hospital treatment and compared with that of two other tryptophan metabolites, namely indolylacetic acid (IAA) and 5-hydroxyindolylacetic acid (5-HIAA). The average excretion of IAcrGly was significantly lower especially between day 3 and 15 post injury. Some alternative explanations of these results are put forward.

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烧伤患者尿中吲哚酰丙烯酰甘氨酸、吲哚乙酸和5-羟基吲哚乙酸的排泄。
吲哚丙烯酰甘氨酸(IAcrGly)是人体尿液的常规成分。除其他情况外,在某些皮肤病中观察到其排泄的变化。本文讨论烧伤中的皮肤损伤。在几周的住院治疗期间,对IAcrGly的排泄进行了跟踪,并与其他两种色氨酸代谢物,即吲哚乙酸(IAA)和5-羟基吲哚乙酸(5-HIAA)进行了比较。IAcrGly的平均排泄量在损伤后3 ~ 15天显著降低。对这些结果提出了一些不同的解释。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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