K M Abdulkadyrov, O A Rukavitsyn, S S Bessmel'tsev, V I Rugal'
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引用次数: 0
Abstract
The authors' investigations found plasmocytic infiltration of bone marrow and marked resorption of bone tissue in patients with multiple myeloma (MM). Instead of the expected reduction in bone marrow volume the latter slightly increased. MM patients have significantly higher quantity of endosteal stromal cells, accumulations of osteoblastic cellular elements considered as initial osteogenesis. A close correlation was revealed between bone tissue volume, number of erythroid elements in bone marrow and red cell count in peripheral blood. Volume of fatty tissues in MM patients is low. MM patients demonstrate pronounced morphofuctional disturbances in hemopoietic microenvironment of bone marrow.
期刊介绍：
The journal publishes original theoretical and clinical studies, lectures, reviews, and practical notes concerning various problems of hematology and clinical and industrial transfusion. The journal provides information on the etiology, pathogenesis, diagnosis and treatment of blood disorders as well as on related non-hematological conditions (internal diseases, poisoning, exposure to ionizing radiation etc.).
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