Weighing the options: criteria for evaluating weight-management programs. The Committee to Develop Criteria for Evaluating the Outcomes of Approaches to Prevent and Treat Obesity.

Obesity research Pub Date : 1995-11-01
J S Stern, J Hirsch, S N Blair, J P Foreyt, A Frank, S K Kumanyika, J H Madans, G A Marlatt, S T St Jeor, A J Stunkard
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Abstract

The United States is experiencing an epidemic of obesity among both adults and children. Approximately 35 percent of women and 31 percent of men age 20 and older are considered obese, as are about one-quarter of children and adolescents. While government health goals for the year 2000 call for no more than 20 percent of adults and 15 percent of adolescents to be obese, the prevalence of this often disabling disease is increasing rather than decreasing. Obesity, of course, is not increasing because people are consciously trying to gain weight. In fact, tens of millions of people in this country are dieting at any one time; they and many others are struggling to manage their weight to improve their appearance, feel better, and be healthier. Many programs and services exist to help individuals achieve weight control. But the limited studies paint a grim picture: those who complete weight-loss programs lose approximately 10 percent of their body weight, only to regain two-thirds of it back within 1 year and almost all of it back within 5 years. These figures point to the fact that obesity is one of the most pervasive public health problems in this country, a complex, multifactorial disease of appetite regulation and energy metabolism involving genetics, physiology, biochemistry, and the neurosciences, as well as environmental, psychosocial, and cultural factors. Unfortunately, the lay public and health-care providers, as well as insurance companies, often view it simply as a problem of willful misconduct--eating too much and exercising too little. Obesity is a remarkable disease in terms of the effort required by an individual for its management and the extent of discrimination its victims suffer. While people often wish to lose weight for the sake of their appearance, public health concerns about obesity relate to this disease's link to numerous chronic diseases that can lead to premature illness and death. The scientific evidence summarized in Chapter 2 suggests strongly that obese individuals who lose even relatively small amounts of weight are likely to decrease their blood pressure (and thereby the risk of hypertension), reduce abnormally high levels of blood glucose (associated with diabetes), bring blood concentrations of cholesterol and triglycerides (associated with cardiovascular disease) down to more desirable levels, reduce sleep apnea, decrease their risk of osteoarthritis of the weight-bearing joints and depression, and increase self-esteem. In many cases, the obese person who loses weight finds that an accompanying comorbidity is improved, its progression is slowed, or the symptoms disappear. Healthy weights are generally associated with a body mass index (BMI; a measure of whether weight is appropriate for height, measured in kg/m2) of 19-25 in those 19-34 years of age and 21-27 in those 35 years of age and older. Beyond these ranges, health risks increase as BMI increases. Health risks also increase with excess abdominal/visceral fat (as estimated by a waist-hip ratio [WHR] > 1.0 for males and > 0.8 for females), high blood pressure (> 140/90), dyslipidemias (total cholesterol and triglyceride concentrations of > 200 and > 225 mg/dl, respectively), non-insulin-dependent diabetes mellitus, and a family history of premature death due to cardiovascular disease (e.g., parent, grandparent, sibling, uncle, or aunt dying before age 50). Weight loss usually improves the management of obesity-related comorbidities or decreases the risks of their development. The high prevalence of obesity in the United States together with its link to numerous chronic diseases leads to the conclusion that this disease is responsible for a substantial proportion of total health-care costs. We estimate that today's health-care costs of obesity exceed $70 billion per year.(ABSTRACT TRUNCATED AT 400 WORDS)

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权衡选择:评估体重管理计划的标准。制定预防和治疗肥胖方法结果评价标准委员会。
美国正在经历成年人和儿童肥胖症的流行。大约35%的20岁及以上的女性和31%的男性被认为肥胖,大约四分之一的儿童和青少年也是如此。虽然政府2000年的保健目标要求成年人肥胖率不超过20%,青少年肥胖率不超过15%,但这种常常致残的疾病的发病率非但没有下降,反而在增加。当然,肥胖并没有增加,因为人们有意识地试图增加体重。事实上,在任何时候,这个国家都有数千万人在节食;她们和其他许多人一样,都在努力控制自己的体重,以改善自己的外表,让自己感觉更好,更健康。现在有许多帮助个人控制体重的项目和服务。但有限的研究描绘了一幅严峻的画面:那些完成减肥计划的人减掉了大约10%的体重,一年内只恢复了三分之二,五年内几乎全部恢复。这些数字表明,肥胖是这个国家最普遍的公共健康问题之一,是一种复杂的、多因素的食欲调节和能量代谢疾病,涉及遗传学、生理学、生物化学和神经科学,以及环境、社会心理和文化因素。不幸的是,非专业的公众和医疗保健提供者以及保险公司往往将其简单地视为故意不当行为的问题——吃得太多,运动太少。就个人管理肥胖所需的努力和肥胖患者遭受歧视的程度而言,肥胖是一种了不起的疾病。虽然人们经常希望减肥是为了他们的外表,但公众对肥胖的关注与这种疾病与许多可能导致过早疾病和死亡的慢性疾病有关。第二章总结的科学证据有力地表明,即使是相对少量的体重减轻,肥胖个体也有可能降低血压(从而降低患高血压的风险),降低异常高的血糖水平(与糖尿病有关),将血液中胆固醇和甘油三酯的浓度(与心血管疾病有关)降低到更理想的水平,减少睡眠呼吸暂停,降低他们患负重关节骨关节炎和抑郁的风险,增强自尊。在许多情况下,减肥的肥胖者发现伴随的合并症得到改善,其进展减慢,或者症状消失。健康体重通常与身体质量指数(BMI;衡量19-34岁者体重与身高是否合适,单位为kg/m2) 19-25, 35岁及以上者体重为21-27。超过这个范围,健康风险会随着BMI的增加而增加。腹部/内脏脂肪过多(男性腰臀比[WHR] > 1.0,女性> 0.8)、高血压(> 140/90)、血脂异常(总胆固醇和甘油三酯浓度分别> 200和> 225 mg/dl)、非胰岛素依赖型糖尿病和因心血管疾病而过早死亡的家族史(例如,父母、祖父母、兄弟姐妹、叔叔或阿姨在50岁之前死亡)也会增加健康风险。减肥通常可以改善与肥胖相关的合并症的管理或降低其发展的风险。肥胖在美国的高流行率,以及它与许多慢性疾病的联系,导致了这样的结论,即这种疾病占医疗保健总费用的很大一部分。我们估计,今天肥胖的医疗保健费用每年超过700亿美元。(摘要删节为400字)
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