[Viral hepatitis type A. Who should be vaccinated?].

G.E.N Pub Date : 1995-10-01
A Albornoz Monque, R C Presilla, B Ascanio Mujica
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Abstract

In order to find out the variations in the Prevalence of HAV ab and identify the persons who should be vaccinated against Hepatitis A virus, we assessed HAV ab to 200 patients without any occupational risk. They were classified by their socioeconomic status; in the following categoris: High (level I n = 0); Medium-High (level II n = 50); Medium-Low (level III, n = 50); Low (level IV, n = 50); and Very Low (level V, n = 50). The percentage of positivity ofr serum HAV ab was: Level II: 12%, Level III: 18%, Level IV: 38% and Level V: 40%. The difference between levels II and III and between levels IV and V was no significant (p > 0.05), but after making a comparation between levels II and III as a group and levels IV V as another one, we found a statistical significant difference (p < 0.005). We concluded: There is a bimodal behavior for the prevalence of serum HAV ab in our study: one group with high prevalence (78%) and another one with low prevalence (30%). The massive Vaccination government programs and the vaccionation in particular cases in the daily medical practice should be done after assessing the personal Socioeconomic status in order to improve the use of this tool and achieve a progressive reduction in the morbiditi and high endemicity of HAV in our city.

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[甲型病毒性肝炎谁应该接种疫苗?]。
为了了解HAV - ab患病率的变化,确定应接种甲型肝炎疫苗的人群,我们对200名无任何职业风险的患者进行了HAV - ab评估。他们根据社会经济地位进行分类;属于以下类别:高(一级n = 0);中高(II级n = 50);中低(III级,n = 50);低水平(IV级,n = 50);和Very Low(水平V, n = 50)。血清HAV抗体阳性率分别为:ⅱ级12%、ⅲ级18%、ⅳ级38%、ⅴ级40%。II级与III级、IV级与V级之间差异无统计学意义(p > 0.05),但将II级与III级作为一组,将IV级与V级作为另一组进行比较,差异有统计学意义(p < 0.005)。我们的结论是:在我们的研究中,血清HAV抗体的患病率呈双峰行为:一组高患病率(78%),另一组低患病率(30%)。政府的大规模疫苗接种计划和日常医疗实践中特殊病例的疫苗接种应在评估个人社会经济状况后进行,以提高对这一工具的使用,实现我市HAV发病率和高流行率的逐步降低。
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[Hepatitis C virus]. [Evaluation of methods for the diagnosis of Helicobacter pylori infection]. [Leptospirosis in Gastroenterology. Study of 14 cases in the Hospital Universitário de Caracas 1984-1994]. [Gastrointestinal stromal sarcoma. Report of a case and review of the literature]. [Von Recklinghausen disease and hepatic neurofibromatosis].
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