Uptake1, Uptake2 and release of 3H-noradrenaline in ovarian artery and in subovarian veno-arterial network of pigs during the ovarian cycle.

Abstract

Uptake1, Uptake2 and the release 3H-noradrenaline in ovarian artery (Oa) and in subovarian veno-arterial network (Sn) of pigs were studied on days 0, 1-2, 13-14 and 16-18 of the ovarian cycle. It was found that Uptake1 in Oa and in Sn was the lowest on the day of ovulation (day 0 = 100%) and then it increased in Sn by 59.9% (p < 0.05) on days 1-2, and was the highest on days 13-14 in Oa = 166.6% (p < 0.05) and in Sn = 208.8% (p < 0.01) and next it decreased on days 16-18 in Oa to 101.5% and in Sn to 136.0% (p < 0.05) in comparison with the day 0. Uptake2 in Oa and Sn was the lowest on the day 0 (100%) and the similarly low on days 16-18 of the estrous cycle, whereas it was markedly higher (p < 0.05) on days 1-2 by 56.2% and by 57.9% in Oa and Sn, and on days 13-14 by 34.1% and by 34.7% in Oa and Sn respectively. The spontaneous release of neuronal radioactivity in Oa was markedly higher only on days 16-18 (by 40.2-53.4%; p < 0.05), whereas release of extraneuronal radioactivity in Oa was the highest on the day O, and significantly lower (p < 0.05) on days 1-2 by 46.6-50.5%, on days 13-14 by 45.0-55.0%, and on days 16-18 by 58.5-61.7%. The spontaneous release of neuronal radioactivity in Sn was the highest on the day O and on days 16-18, whereas it was lower (p < 0.05) on days 1-2 by 53.7-55.6% and on days 13-14 by 36.0-46.4%. It seems that Uptake1 increase and simultaneously the decrease of NA neuronal release in subovarian veno-arterial network during luteal phase can be one of condition mechanisms leading to diminution of ovarian vessels tension and rise of ovarian blood flow.