An on-demand system of delivering pre-mixed inspiratory gas for use during physical activity.

A D Taylor, R Bronks
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Abstract

This study analysed the effectiveness of an on-demand system of supplying pre-mixed inspiratory gases to subjects under working conditions. A supply of pre-mixed inspiratory gas is often required in order to study the effects of acute hypoxia/hyperoxia on numerous physiological variables whilst normobaric pressure is maintained. The principle aim of this investigation was to determine if the introduction of the on-demand system resulted in any changes in minute ventilation (VE), oxygen consumption (VO2), respiratory rate (RR), tidal volume (VT) or endurance performance during incremental cycle ergometry to exhaustion. Trained male subjects participated in the study (n = 9). The subjects completed two incremental trials on a Monark cycle ergometer. The trials commenced at a power output of 60W implementing a 30 W.4 min-1 work increment. In one trial the subjects inspired ambient room air as per normal VO2max testing, whilst in the other trial the subjects inspired compressed air supplied from high pressure cylinders using a demand valve. Trial order was randomised. Raw data (time, heart rate, VI[ATPS], respiratory rate, tidal volume, FEO2 and FECO2) were recorded on line every 15 seconds. No differences in gas exchange variables were apparent at rest (VO2 VE RR, VT) nor during submaximal work between normal and on-demand trials. VO2max, VEmax and physical performance were also not significantly different between trials. On the basis of these findings, it was suggested that the on-demand system of supplying inspiratory gas resulted in minimal changes in gas exchange variables and performance during incremental work. Using this system of gas supply researchers can effectively supply subjects with premixed gas for little financial expense.

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一种按需输送用于身体活动期间的预混合吸入气体的系统。
本研究分析了在工作条件下按需提供预混合吸入气体系统的有效性。为了研究急性缺氧/高氧对许多生理变量的影响,在维持常压的情况下,通常需要提供预混合的吸入气体。本研究的主要目的是确定按需系统的引入是否会导致在增量周期测量至衰竭期间的分钟通气(VE)、耗氧量(VO2)、呼吸速率(RR)、潮气量(VT)或耐力表现的任何变化。训练有素的男性受试者参加了这项研究(n = 9)。受试者在Monark自行车计力器上完成了两次增量试验。试验开始时的输出功率为60W,工作增量为30w。在一项试验中,受试者按照正常的VO2max测试吸入环境室内空气,而在另一项试验中,受试者使用需求阀吸入高压钢瓶供应的压缩空气。试验顺序随机化。每隔15秒在线记录一次原始数据(时间、心率、VI[ATPS]、呼吸频率、潮气量、FEO2和FECO2)。在正常和按需试验中,休息时的气体交换变量(VO2、VE、RR、VT)和次最大工作时的气体交换变量没有明显差异。试验间VO2max、VEmax和体能表现也无显著差异。基于这些发现,我们认为按需供气系统在增量工作过程中对气体交换变量和性能的影响最小。利用该供气系统,研究人员可以有效地为实验对象提供预混气,且费用较低。
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