[Determination of canine thyroid stimulating hormone (cTSH) in blood serum of dogs and its reaction to the TRH stimulation test].

Abstract

The introduction of the determination of canine TSH in the blood serum of the dog means a substantial enrichment in the diagnosis of thyroid disease. In the present study the basic value of serum c-TSH and its maximal increase after intravenous injection of 200 micrograms TRH per dog were determined. The basic value was 0.18 +/- 0.11 ng/ml, the maximal increase was reached between 15 and 30 minutes after injection of TRH and was 0.53 +/- 0.24 ng/ml. In two hypothyroidal dogs the basic values of T4 were 1.1 and 0.56 microgram/dl and of fT4 0.19 and 0.15 ng/dl, respectively. Their TSH concentration was 1.35 and 4.0 ng/ml, respectively.