Meningococcal disease in the Republic of Ireland: 1995.

I Fogarty, M T Cafferkey, A C Moloney
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Abstract

Two hundred and nine culture confirmed cases of meningococcal disease were reported in the Republic of Ireland in 1995, using a new laboratory based surveillance system. The reported rate of 5.9/100000 population is one of the highest in western Europe, but the rate differed widely between regions. Fifty-three per cent of cases were female. Half of the cases occurred in four months (January, February, March, and December). Nineteen cases (9%) died. The highest age specific incidence was in infancy (under 1 year). Infections with serogroup B accounted for 105 cases (54%) and serogroup C 87 cases (45%). We estimate that up to 30% of cases of meningococcal disease may be preventable when conjugate meningococcal group C vaccines become available, but cost benefit analyses will be required to determine how they should be employed.

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爱尔兰共和国脑膜炎球菌病:1995年。
1995年,爱尔兰共和国利用一种新的实验室监测系统报告了239例经培养确认的脑膜炎球菌病病例。据报道,每10万人中有5.9人是西欧最高的人口之一,但各地区之间的比例差异很大。53%的病例是女性。半数病例发生在4个月内(1月、2月、3月和12月)。死亡19例(9%)。年龄特异性发病率最高的是婴儿(1岁以下)。血清B组感染105例(54%),血清C组感染87例(45%)。我们估计,当C组脑膜炎球菌结合疫苗可用时,高达30%的脑膜炎球菌病病例是可以预防的,但需要进行成本效益分析,以确定如何使用这些疫苗。
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