[Determination of crude drugs in the pharmacopoeia].

H Suzuki, M Satake
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Abstract

The determination of crude drugs by high performance liquid chromatograph (HPLC) method was introduced to the Japanese Pharmacopoeia (JP) 12 for the first time. At JP 13, another HPLC methods were established for eight kinds of crude drugs and relative medicines. Special conception is used in the determination of crude drugs, different from chemical medicines. Determinations were classified to two methods: "assay" and "component determination" according to standards. "The Japanese Reference Standard" or "Reagent for assay" is used in assay, and "Reagent for component determination". is used in component determination. In addition, the analysis and the dryness of crude drug were discussed because they were important to evaluate the result of analysis exactly.

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[药典中生药的测定]。
高效液相色谱法(HPLC)在日本药典(JP)第12版中首次引入。在jp13建立了8种药材及其相关药物的HPLC测定方法。不同于化学药品,生药的测定采用了特殊的概念。按标准分为“含量测定”和“成分测定”两种方法。在分析中使用“日本参考标准”或“测定试剂”,“成分测定试剂”。用于成分测定。此外,还讨论了分析和干燥度是准确评价分析结果的重要因素。
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