Malaria sporozoites and chylomicron remnants compete for binding sites in the liver.

Behring Institute Mitteilungen Pub Date : 1997-03-01
V Nussenzweig
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Abstract

Like Malaria sporozoites and the circumsporozoite protein, remnants of lipoproteins are rapidly cleared from the circulation and enter hepatocytes. Here we review the evidence that the same set of liver heparan sulfate proteoglycans are the initial binding sites of malaria sporozoites and the lipoprotein remnants.

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疟疾孢子子和乳糜微粒残余物在肝脏中竞争结合位点。
就像疟疾孢子子和环孢子子蛋白一样,脂蛋白的残余物会迅速从循环中清除并进入肝细胞。在此,我们回顾了同一组硫酸肝素蛋白聚糖是疟疾孢子子和脂蛋白残体的初始结合位点的证据。
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The role of chemokines and accessory cells in the immunoregulation of cutaneous leishmaniasis. Schistosoma mansoni infection induces a type 1 CD8+ cell response. Malaria sporozoites and chylomicron remnants compete for binding sites in the liver. The role of the cytoskeleton in host cell invasion by Toxoplasma gondii. Reactivation of chronic toxoplasmosis: is there a link to strain-specific differences in the parasite?
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