[Velocity of erosion and factors that modify human tooth demineralization in vitro].

R G Lissera, E R Luna Maldonado De Yankilevich, L J Battellino
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Abstract

Velocity of erosion on human teeth exposed to a carbonated beverage as a function of time and temperature has been studied in vitro, as well as the effect of the experimental formation of a acquired pellicle and the influence of the inclusion of either F or saliva on the dissolving capacity of beverage. During the first stage of exposition, erosion as a function of time showed a biphasic curve, being the rate low during the first 10 minutes time; thereafter, velocity increased and remained stable until the 60 minute incubation period finished. At the second stage, demineralization followed a monophasic curve, displaying a stable rate until the end of it. At the initial stage, molar ratio Ca/P was much less than that corresponding to hydroxyapatite (approximately 1.67); however, as exposition to erosive beverage was prolonged, the former ratio reached values compatible with this mineral species. F or saliva incorporation together with the experimental formation of the acquired pellicle significatively reduced beverage demineralizing capacity (p < 0.0001). This finding introduces the possibility of attenuating such erosive capacity of carbonated beverages by including not excessively toxic fluoride quantities.

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[体外侵蚀速度及影响人类牙齿脱矿的因素]。
我们在体外研究了人类牙齿接触碳酸饮料时的腐蚀速度与时间和温度的关系,以及实验形成的获得性膜的影响,以及含F或唾液对饮料溶解能力的影响。在暴露的第一阶段,侵蚀作为时间的函数表现为双相曲线,在前10分钟内速率较低;此后,速度增加并保持稳定,直到60分钟的潜伏期结束。在第二阶段,脱矿遵循单相曲线,并呈现稳定的速率直至结束。在初始阶段,Ca/P的摩尔比远小于羟基磷灰石(约为1.67);然而,随着腐蚀饮料暴露时间的延长,前者的比值达到了与该矿物相适应的值。唾液的掺入和获得性膜的实验形成显著降低了饮料的脱矿能力(p < 0.0001)。这一发现提出了通过加入不过量毒性的氟化物量来减弱碳酸饮料这种侵蚀能力的可能性。
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