[Changes in lipid metabolism during oxidative stress caused by cobalt chloride injection].

Abstract

The cobalt chloride influence on rat liver and serum blood lipids and lipoproteins content and composition was investigated. The data obtained show that the cobalt chloride injection leads to the oxidative stress development and to activation of lipid transport and metabolism. It has been shown that there is system of lipids homeostasis in the organism and it is activated under conditions of oxidative stress. The system blood lipoproteins and liver lipoproteins was found to participate in metabolism adaptation on oxidative stress and in maintenance of biological membranes structure and functioning.