[Regulatory components of the eukaryotic translation apparatus in normal states and after exposure to ionizing radiation].

R P Vynohradova, O F Zudina, O V Khudiakova, S P Imedadze
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Abstract

The comparative analysis of content prostaglandins E2, F2 alpha and cAMP, cGMP in the compositions of the high-molecular aminoacyl-tRNA synthetase complexes and endoplasmic reticulum vesicules from the rat liver has been carried out. The influence of lethal and sublethal X-ray doses on the levels of cyclic nucleotides and prostaglandins has been studied. Cyclic nucleotides and prostaglandins proved to be rapid and high sensitive transmitters of ionizing radiation influence on the eukaryotic translation apparatus.

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[正常状态和电离辐射暴露后真核生物翻译装置的调节成分]。
比较分析了大鼠肝脏高分子氨基酰基- trna合成酶复合物和内质网小泡组成物中前列腺素E2、F2 α和cAMP、cGMP的含量。已经研究了致死和亚致死x射线剂量对环核苷酸和前列腺素水平的影响。环核苷酸和前列腺素被证明是电离辐射对真核生物翻译装置影响的快速和高灵敏度的递质。
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