Prognosis of surgically treated lung cancer.

Annales chirurgiae et gynaecologiae Pub Date : 1999-01-01
J T Ikonen, J P Salenius, A Ojala, J Mattila, H Riekkinen, T Wigren
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Abstract

Background and aims: This retrospective study clarifies the prognosis of surgically treated lung cancer in a teaching university hospital.

Material and methods: During a four year period 141 patients were operated for lung cancer in a teaching university hospital. After five years follow up the case records were analysed. The operative and microscopical findings were classified using the AJC pTNM staging system and WHO's histologic classification of lung tumours. There were 120 (85 %) male and 21 (15 %) female. The median age for males was 62 years and females 64 years; range was 29 to 76 years for both sexes.

Results and conclusions: The perioperative mortality of all patients was 5,0 %, of 84 patients operated with lobectomy 2.4 %, of 32 patients operated with pneumectomy 15,6 %, and of 25 patients operated with explorative thoracotomy 0 %, respectively. The five year survival of all patients was 33 % including perioperative mortality. The survival was significantly better for 83 patients with stage I disease (49 %) than 17 stage II (6 %), 24 stage IIIa (20.8 %), and 17 stage IIIb or IV disease (0 %). The survival was significantly better after lobectomy (44.1 %) than after pneumectomy (25.0 %) or explorative thoracotomy (8.0 %). Our study shows the good effect of surgery in stage I, and confirms it's usefulness in stage IIIa lung cancer. The histologic types of tumours did not affect survival.

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手术治疗肺癌的预后。
背景与目的:回顾性研究某大学附属教学医院手术治疗肺癌的预后。材料与方法:对141例肺癌患者在某大学附属教学医院进行手术治疗。经过5年的随访,对病例记录进行了分析。使用AJC pTNM分期系统和WHO肺肿瘤的组织学分级对手术和显微镜检查结果进行分类。其中男性120例(85%),女性21例(15%)。男性的中位年龄为62岁,女性为64岁;男性和女性的年龄范围在29岁到76岁之间。结果与结论:所有患者围手术期死亡率为5.0%,84例肺叶切除术患者死亡率为2.4%,32例全肺切除术患者死亡率为15.6%,25例探查性开胸手术患者死亡率为0%。包括围手术期死亡率在内,所有患者的5年生存率为33%。83例I期患者(49%)的生存率明显优于17例II期患者(6%)、24例IIIa期患者(20.8%)和17例IIIb或IV期患者(0%)。肺叶切除术(44.1%)的生存率明显优于全肺切除术(25.0%)或探索性开胸手术(8.0%)。我们的研究显示手术治疗I期肺癌的效果良好,并证实了手术治疗IIIa期肺癌的有效性。肿瘤的组织学类型不影响生存。
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