Compounds labelled with short-lived beta(+)-emitting radionuclides and some applications in life sciences. The importance of time as a parameter.

B Långström, T Kihlberg, M Bergström, G Antoni, M Björkman, B H Forngren, T Forngren, P Hartvig, K Markides, U Yngve, M Ogren
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引用次数: 77

Abstract

Some examples of recent development of the synthesis of compounds labelled with short-lived beta(+)-emitting radionuclides will be discussed with an emphasis on the importance of time in selecting a synthetic strategy. Furthermore the use of such labelled compounds to monitor certain processes in areas within the field of analytical chemistry and in various applications in drug development will be presented.

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用短寿命β(+)放射核素标记的化合物及其在生命科学中的一些应用。时间作为参数的重要性。
本文将讨论用短寿命β(+)放射核素标记的化合物的合成最近发展的一些例子,重点是时间在选择合成策略方面的重要性。此外,还将介绍在分析化学领域和在药物开发中的各种应用中使用这种标记化合物来监测某些过程。
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The solubilities of denatured proteins in different organic solvents. Compounds labelled with short-lived beta(+)-emitting radionuclides and some applications in life sciences. The importance of time as a parameter. Hydrolysis of organophosphorus nerve agent soman by the monoclonal antibodies elicited against an oxyphosphorane hapten. Syntheses of some polyunsaturated sulfur- and oxygen-containing fatty acids related to eicosapentaenoic and docosahexaenoic acids. Preparation and antimicrobial studies of acyclic sulfamates.
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