Allergic contact dermatitis to polyethylene glycol and nitrofurazone.

S C Guijarro, J Sánchez-Pérez, A García-Díez
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Abstract

We report a case of worsening dermatitis after the application of an antibiotic ointment (Furacin) containing furazone and polyethylene glycol. Patch tests to nickel sulfate, potassium dischromate, chloride cobalt, Furacin, nitrofurazone 1% petrolatum, polyethylene glycol mix 4% petrolatum, polyethylene glycol (PEG) 300 4% petrolatum, and PEG 400 as is (ai) were positive. The use of topical agents containing nitrofurazone or polyethylene glycol on damaged skin may predispose to contact allergy. We discuss the sensitizing properties of nitrofurazone and polyethylene glycol.

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对聚乙二醇和硝基呋喃酮的过敏性接触性皮炎。
我们报告一个病例恶化皮炎后,应用抗生素软膏(呋喃醌)含有呋喃酮和聚乙二醇。对硫酸镍、重铬酸钾、氯化钴、呋喃星、硝基呋喃酮1%凡士林、聚乙二醇混合物4%凡士林、聚乙二醇(PEG) 300 4%凡士林和聚乙二醇400原液(ai)进行斑贴试验均为阳性。在受损皮肤上使用含有硝基呋喃酮或聚乙二醇的局部药物可能易导致接触性过敏。讨论了硝基呋喃酮和聚乙二醇的增敏性能。
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