{"title":"Synthesis and biological evaluation of 9-(beta-L-arabinofuranosyl)adenine.","authors":"V Boudou, J L Imbach, G Gosselin","doi":"10.1080/07328319908044620","DOIUrl":null,"url":null,"abstract":"<p><p>For the first time, the stereospecific synthesis of 9-(beta-L-arabinofuranosyl) adenine was carried out. Unfortunately, and unlike its \"natural\" D-counterpart Vidarabine, this L-enantiomer did not show significant activity when evaluated against a broad range of viruses.</p>","PeriodicalId":19222,"journal":{"name":"Nucleosides & nucleotides","volume":"18 11-12","pages":"2463-73"},"PeriodicalIF":0.0000,"publicationDate":"1999-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/07328319908044620","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nucleosides & nucleotides","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/07328319908044620","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
For the first time, the stereospecific synthesis of 9-(beta-L-arabinofuranosyl) adenine was carried out. Unfortunately, and unlike its "natural" D-counterpart Vidarabine, this L-enantiomer did not show significant activity when evaluated against a broad range of viruses.
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