Color duplex scanning for the identification of extracranial atherosclerosis in patients with suspected coronary artery disease.

Cardiologia (Rome, Italy) Pub Date : 1999-12-01
M Zimarino, M Soccio, M Scarpignato, V Venarucci, L Cappelletti, A Di Crecchio, R Cini, S Gallina, A M Calafiore, A Barsotti
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Abstract

Background: The presence of extracranial artery disease has been used as a predictor of coronary artery disease (CAD). The present study was conducted to test the prevalence of extracranial artery disease among patients with suspected CAD.

Methods: Among candidates for coronary arteriography, 400 consecutive patients (mean age 63 +/- 11 years, 78% males, 22% females) underwent color duplex ultrasound of carotid arteries.

Results: Extracranial artery disease was documented in 60 patients (15%), CAD in 309 patients (77%). Patients with extracranial artery disease were significantly older (p < 0.001), smoked a higher amount of pack-years (p < 0.001), showed a higher incidence of diabetes (p < 0.01), hypertension (p < 0.05) and CAD (p < 0.05) when compared to extracranial artery disease-free subjects. Plotting age against extracranial artery disease and CAD distribution, extracranial artery disease occurred later in life than CAD (p < 0.001). The best cut-off point of age for predicting extracranial artery disease was 68 years. Carotid angiography was performed in 114 patients after cardiac catheterization (k = 0.8044 with color duplex scanning).

Conclusions: Extracranial artery disease is frequent among patients undergoing coronary arteriography. Carotid ultrasound screening is useful in older patients.

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彩色双工扫描对疑似冠状动脉疾病患者颅内外动脉粥样硬化的鉴别价值。
背景:颅外动脉疾病的存在已被用作冠状动脉疾病(CAD)的预测因子。本研究旨在检测疑似冠心病患者颅内外动脉疾病的患病率。方法:在冠状动脉造影候选者中,连续400例患者(平均年龄63 +/- 11岁,男性78%,女性22%)行颈动脉彩超检查。结果:颅外动脉病变60例(15%),冠心病309例(77%)。与无颅外动脉疾病的患者相比,有颅外动脉疾病的患者年龄明显增加(p < 0.001),吸烟包年数量明显增加(p < 0.001),糖尿病(p < 0.01)、高血压(p < 0.05)和CAD (p < 0.05)的发病率明显增加。绘制年龄与颅外动脉疾病和CAD分布的关系图,颅外动脉疾病发生的时间比CAD晚(p < 0.001)。预测颅外动脉疾病的最佳年龄分界点为68岁。114例心导管术后行颈动脉造影(彩色双工扫描k = 0.8044)。结论:颅外动脉病变是冠状动脉造影患者的常见病。颈动脉超声筛查对老年患者有用。
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