Puboprostatic ligament sparing radical retropubic prostatectomy.

Seminars in urologic oncology Pub Date : 2000-02-01
J P Jarow
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Abstract

Prostate cancer is the most common solid malignancy and the second most common cause of cancer death in man. Radical prostatectomy is the therapeutic modality that currently provides the best long-term biochemical relapse-free survival rate. Yet many patients select alternative forms of therapy or no therapy at all because of fears that treatment will significantly alter quality of life. Urinary incontinence following radical prostatectomy has a significant deleterious effect on quality of life and, unfortunately, is much more prevalent following surgery compared with other treatment modalities, such as radiation therapy. Many efforts have been undertaken to avoid this complication with only modest success achieved. These include creation of a neobladder neck, bladder neck preservation, periurethral injection of bulking agents, and anterior urethropexy. A technique for radical retropubic prostatectomy that spares the puboprostatic ligaments, which preserves the normal anterior support of the urethra, is described herein. The outcome following this procedure demonstrates more rapid return of full urinary continence following radical prostatectomy in a controlled study. However, the "Holy Grail" of complete eradication of urinary incontinence following radical prostatectomy has not been achieved.

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保留耻骨前列腺韧带根治性耻骨后前列腺切除术。
前列腺癌是最常见的实体恶性肿瘤,也是导致人类癌症死亡的第二大常见原因。根治性前列腺切除术是目前提供最佳长期生化无复发生存率的治疗方式。然而,由于担心治疗会显著改变生活质量,许多患者选择其他形式的治疗或根本不接受治疗。根治性前列腺切除术后的尿失禁对生活质量有显著的有害影响,不幸的是,与其他治疗方式(如放射治疗)相比,手术后尿失禁更为普遍。为避免这种复杂情况作出了许多努力,但只取得了有限的成功。这些包括新膀胱颈部的形成、膀胱颈部的保存、尿道周围注射膨胀剂和前路尿道固定术。本文描述了一种根治性耻骨后前列腺切除术的技术,该技术保留了耻骨前列腺韧带,从而保留了尿道的正常前支。在一项对照研究中,这种手术的结果表明根治性前列腺切除术后完全尿失禁的恢复速度更快。然而,根治性前列腺切除术后完全根除尿失禁的“圣杯”尚未实现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Management of stage I nonseminomatous germ-cell tumors. Controversies in the management of testicular seminoma. Contralateral testicular biopsy procedure in patients with unilateral testis cancer: is it indicated? Adjuvant chemotherapy for stage II nonseminomatous germ-cell tumors. Chemotherapy for good-risk germ-cell tumors.
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