Efficacy of, and quality of life after antireflux surgery.

H Lönroth
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Abstract

A complete evaluation of reflux operations depends on measurements of preoperative and postoperative clinical symptoms such as dysphagia and heartburn, assessment of quality of life and objective measurements of 24-hour oesophageal pH monitoring and manometry. Quality of life can be measured with questionnaires such as the Gastrointestinal Symptom Rating Scale (GSRS), the Psychological General Wellbeing Index (PGWB) and the Reflux-related Visual Analogue Scale (RVAS). Failure of treatment is indicated by persistent symptoms such as heartburn, need for antisecretory medication, and new symptoms such as severe dysphagia. The advantages of laparoscopic operations are mainly a quick recovery and a good cosmetic results. Good short-term cure of symptoms is reported in 90%-97% of patients who have laparoscopic fundoplication. The long-term clinical outcome is equal to or better than that of open operations. Several clinical studies have shown that laparoscopic fundoplication is effective in improving symptom ratings and the quality of life.

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抗反流手术后的疗效和生活质量。
对反流手术的完整评估取决于术前和术后临床症状的测量,如吞咽困难和胃灼热,生活质量的评估以及24小时食管pH值监测和血压测量的客观测量。生活质量可通过胃肠道症状评定量表(GSRS)、心理一般健康指数(PGWB)和反流相关视觉模拟量表(RVAS)等问卷进行测量。治疗失败的迹象是持续的症状,如胃灼热,需要抗分泌药物,以及新的症状,如严重的吞咽困难。腹腔镜手术的优点主要是恢复快,美容效果好。据报道,90%-97%的腹腔镜下盆底切除术患者症状短期治愈。远期临床效果等于或优于开放手术。一些临床研究表明,腹腔镜下盆底折叠术在改善症状评分和生活质量方面是有效的。
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