Surgical treatment of recurrent differentiated thyroid carcinoma.

Andrea Dávila-Cervantes, Rosa Gamino, Ofelia González, Miguel F Herrera
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引用次数: 0

Abstract

Objective: To describe our experience of treating recurrent thyroid carcinoma.

Design: Retrospective study of casenotes.

Setting: Teaching hospital, Mexico.

Subjects: 20 patients who developed recurrences of 273 who presented with well-differentiated thyroid carcinoma between 1991 and 1999.

Main outcome measures: Presentation, management, morbidity, and mortality.

Results: There were 18 men and 2 women, median age 51 years (range 28-75). 13 were treated initially by total thyroidectomy and 7 with less than total resection. 16 were given ablative doses of 311I. The median time between initial resection and recurrence was 3 years (range 1-6). The sites of recurrence were cervical lymph nodes (n = 12), thyroid bed (n = 3), or both (n = 5). During a median of 3 years 10 patients were free of disease and 2 had died.

Conclusions: Well-differentiated thyroid cancer usually recurs in the cervical lymph nodes. Further resection offers a high cure rate.

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复发分化型甲状腺癌的手术治疗。
目的:总结治疗复发性甲状腺癌的经验。设计:个案的回顾性研究。环境:墨西哥教学医院。研究对象:20例复发的273例1991年至1999年间表现为分化良好的甲状腺癌患者。主要结局指标:表现、治疗、发病率和死亡率。结果:男性18例,女性2例,中位年龄51岁(28 ~ 75岁)。13例采用全甲状腺切除术,7例不完全切除。16只小鼠给予311I烧蚀剂量。从初次切除到复发的中位时间为3年(范围1-6年)。复发部位为颈部淋巴结(n = 12),甲状腺床(n = 3),或两者均有(n = 5)。在中位3年期间,10例患者无疾病,2例死亡。结论:高分化甲状腺癌常复发于颈部淋巴结。进一步切除的治愈率很高。
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