Fine needle aspiration cytology of solid papillary carcinoma of the breast. A report of four cases.

IF 1.7 4区医学 Q3 PATHOLOGY Acta Cytologica Pub Date : 2003-03-01 DOI:10.1159/000326513

David Hardisson, Pilar González-Peramato, Cristian Perna, Jesús Cuevas, Jaime Sánchez-Fernández de la Vega

{"title":"Fine needle aspiration cytology of solid papillary carcinoma of the breast. A report of four cases.","authors":"David Hardisson, Pilar González-Peramato, Cristian Perna, Jesús Cuevas, Jaime Sánchez-Fernández de la Vega","doi":"10.1159/000326513","DOIUrl":null,"url":null,"abstract":"Background: Solid papillary carcinoma of the breast (SPCB) is a distinctive form of papillary carcinoma that tends to occur in older women and usually has a favorable prognosis.Cases: We report the cytologic and histologic findings in four cases of SPCB. All but one of the patients were elderly women (mean age, 66 years). Three patients presented with breast masses, and one patient presented with a breast mass and nipple discharge. Cytology demonstrated moderately to highly cellular smears with irregular groups of predominantly monolayered epithelium composed of small, polygonal or cuboidal cells with eosinophilic cytoplasm and rounded, eccentrically placed nuclei. Papillalike clusters with thin, fibrovascular cores were also observed. Immunocytochemical expression of synaptophysin was present in two cases. The diagnosis of SPBC was subsequently confirmed histologically and immunohistochemically.Conclusion: The FNA of SPCB displays some features that may be helpful in its correct identification preoperatively.","PeriodicalId":6959,"journal":{"name":"Acta Cytologica","volume":"47 2","pages":"259-64"},"PeriodicalIF":1.7000,"publicationDate":"2003-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000326513","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Cytologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000326513","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PATHOLOGY","Score":null,"Total":0}

引用次数: 10

Abstract

Background: Solid papillary carcinoma of the breast (SPCB) is a distinctive form of papillary carcinoma that tends to occur in older women and usually has a favorable prognosis.

Cases: We report the cytologic and histologic findings in four cases of SPCB. All but one of the patients were elderly women (mean age, 66 years). Three patients presented with breast masses, and one patient presented with a breast mass and nipple discharge. Cytology demonstrated moderately to highly cellular smears with irregular groups of predominantly monolayered epithelium composed of small, polygonal or cuboidal cells with eosinophilic cytoplasm and rounded, eccentrically placed nuclei. Papillalike clusters with thin, fibrovascular cores were also observed. Immunocytochemical expression of synaptophysin was present in two cases. The diagnosis of SPBC was subsequently confirmed histologically and immunohistochemically.

Conclusion: The FNA of SPCB displays some features that may be helpful in its correct identification preoperatively.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

乳腺实性乳头状癌的细针抽吸细胞学。四例报告。

背景:乳腺实体乳头状癌(SPCB)是一种独特的乳头状癌，多发生于老年妇女，通常预后良好。病例:我们报告4例SPCB的细胞学和组织学表现。除1例患者外，其余患者均为老年妇女(平均年龄66岁)。3例患者表现为乳房肿块，1例患者表现为乳房肿块和乳头溢液。细胞学表现为中度至高度细胞涂片，不规则群为主的单层上皮，由小的、多边形或立方体细胞组成，细胞质嗜酸性，细胞核圆形，偏心放置。还观察到具有薄纤维血管核心的乳头状簇。两例均可见synaptophysin的免疫细胞化学表达。SPBC的诊断随后经组织学和免疫组织化学证实。结论:SPCB的FNA表现出一些特点，有助于术前正确鉴别。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Acta Cytologica 生物-病理学

CiteScore

3.70

自引率

11.10%

发文量

审稿时长

4-8 weeks

期刊介绍： With articles offering an excellent balance between clinical cytology and cytopathology, ''Acta Cytologica'' fosters the understanding of the pathogenetic mechanisms behind cytomorphology and thus facilitates the translation of frontline research into clinical practice. As the official journal of the International Academy of Cytology and affiliated to over 50 national cytology societies around the world, ''Acta Cytologica'' evaluates new and existing diagnostic applications of scientific advances as well as their clinical correlations. Original papers, review articles, meta-analyses, novel insights from clinical practice, and letters to the editor cover topics from diagnostic cytopathology, gynecologic and non-gynecologic cytopathology to fine needle aspiration, molecular techniques and their diagnostic applications. As the perfect reference for practical use, ''Acta Cytologica'' addresses a multidisciplinary audience practicing clinical cytopathology, cell biology, oncology, interventional radiology, otorhinolaryngology, gastroenterology, urology, pulmonology and preventive medicine.