{"title":"Preparation of fluorescence ethosomes based on quantum dots and their skin scar penetration properties","authors":"Rong He, Da-xiang Cui, Feng Gao","doi":"10.1016/j.matlet.2009.05.003","DOIUrl":null,"url":null,"abstract":"<div><p><span>In this study, the fluorescence ethosomes (ES-QDs) composed of hydrophilic CdTe fluorescent clusters (quantum dots, QDs) were prepared. The prepared ES-QDs with even particle size were obtained by extruding the vesicles through polycarbonate membrane filters and were characterized by </span>TEM<span> SEM HPPS and photoluminescence spectra. Their in vitro experiments to penetrate into human skin scar were performed by using the Franz diffusion cell. Results showed that the prepared ES-QDs not only have the properties of ethosome to penetrate the skin scar tissues but also have the fluorescence labeling properties of the quantum dots. The prepared ES-QDs have potential clinical application in therapy of skin scar.</span></p></div>","PeriodicalId":384,"journal":{"name":"Materials Letters","volume":"63 20","pages":"Pages 1662-1664"},"PeriodicalIF":2.7000,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.matlet.2009.05.003","citationCount":"30","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Letters","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167577X09003413","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 30
Abstract
In this study, the fluorescence ethosomes (ES-QDs) composed of hydrophilic CdTe fluorescent clusters (quantum dots, QDs) were prepared. The prepared ES-QDs with even particle size were obtained by extruding the vesicles through polycarbonate membrane filters and were characterized by TEM SEM HPPS and photoluminescence spectra. Their in vitro experiments to penetrate into human skin scar were performed by using the Franz diffusion cell. Results showed that the prepared ES-QDs not only have the properties of ethosome to penetrate the skin scar tissues but also have the fluorescence labeling properties of the quantum dots. The prepared ES-QDs have potential clinical application in therapy of skin scar.
期刊介绍：
Materials Letters has an open access mirror journal Materials Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
Materials Letters is dedicated to publishing novel, cutting edge reports of broad interest to the materials community. The journal provides a forum for materials scientists and engineers, physicists, and chemists to rapidly communicate on the most important topics in the field of materials.
Contributions include, but are not limited to, a variety of topics such as:
• Materials - Metals and alloys, amorphous solids, ceramics, composites, polymers, semiconductors
• Applications - Structural, opto-electronic, magnetic, medical, MEMS, sensors, smart
• Characterization - Analytical, microscopy, scanning probes, nanoscopic, optical, electrical, magnetic, acoustic, spectroscopic, diffraction
• Novel Materials - Micro and nanostructures (nanowires, nanotubes, nanoparticles), nanocomposites, thin films, superlattices, quantum dots.
• Processing - Crystal growth, thin film processing, sol-gel processing, mechanical processing, assembly, nanocrystalline processing.
• Properties - Mechanical, magnetic, optical, electrical, ferroelectric, thermal, interfacial, transport, thermodynamic
• Synthesis - Quenching, solid state, solidification, solution synthesis, vapor deposition, high pressure, explosive
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