{"title":"The purification and characterization of a new active immunizing polysaccharide prepared from Staphylococcus aureus","authors":"Theodore H. Haskell, Stephen Hanessian","doi":"10.1016/0926-6526(64)90048-5","DOIUrl":null,"url":null,"abstract":"<div><p>A new acidic polysaccharide which produces an immunogenic response in mice, dogs and man has been obtained in pure form from acid hydrolysates of <em>Staphylococcus aureus</em> cells. Structural studies show the antigen to be composed of <span>d</span>-glucosaminuronic acid and <span>l</span>-alanine with <em>O</em>- and <em>N</em>-acetyl substitution.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 1","pages":"Pages 35-41"},"PeriodicalIF":0.0000,"publicationDate":"1964-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90048-5","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0926652664900485","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
A new acidic polysaccharide which produces an immunogenic response in mice, dogs and man has been obtained in pure form from acid hydrolysates of Staphylococcus aureus cells. Structural studies show the antigen to be composed of d-glucosaminuronic acid and l-alanine with O- and N-acetyl substitution.
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