Non-invasive biomedical research and diagnostics enabled by innovative compact lasers

IF 7.4 1区 物理与天体物理 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Progress in Quantum Electronics Pub Date : 2017-11-01 DOI:10.1016/j.pquantelec.2017.10.001
Karina S. Litvinova , Ilya E. Rafailov , Andrey V. Dunaev , Sergei G. Sokolovski , Edik U. Rafailov
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引用次数: 14

Abstract

For over half a century, laser technology has undergone a technological revolution. These technologies, particularly semiconductor lasers, are employed in a myriad of fields. Optical medical diagnostics, one of the emerging areas of laser application, are on the forefront of application around the world. Optical methods of non- or minimally invasive bio-tissue investigation offer significant advantages over alternative methods, including rapid real-time measurement, non-invasiveness and high resolution (guaranteeing the safety of a patient). These advantages demonstrate the growing success of such techniques.

In this review, we will outline the recent status of laser technology applied in the biomedical field, focusing on the various available approaches, particularly utilising compact semiconductor lasers. We will further consider the advancement and integration of several complimentary biophotonic techniques into single multimodal devices, the potential impact of such devices and their future applications. Based on our own studies, we will also cover the simultaneous collection of physiological data with the aid a multifunctional diagnostics system, concentrating on the optimisation of the new technology towards a clinical application. Such data is invaluable for developing algorithms capable of delivering consistent, reliable and meaningful diagnostic information, which can ultimately be employed for the early diagnosis of disease conditions in individuals from around the world.

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创新的紧凑型激光器使非侵入性生物医学研究和诊断成为可能
半个多世纪以来,激光技术经历了一场技术革命。这些技术,特别是半导体激光器,被应用于许多领域。光学医学诊断是激光应用的新兴领域之一,在世界范围内处于应用前沿。光学方法的非或微创生物组织调查提供了显著的优势比其他方法,包括快速实时测量,非侵入性和高分辨率(保证患者的安全)。这些优点表明这种技术越来越成功。在这篇综述中,我们将概述激光技术在生物医学领域的应用现状,重点介绍各种可用的方法,特别是利用紧凑的半导体激光器。我们将进一步考虑将几种互补的生物光子技术的进步和集成到单个多模态器件中,这些器件的潜在影响及其未来的应用。基于我们自己的研究,我们也将涵盖在多功能诊断系统的帮助下同时收集生理数据,专注于优化新技术的临床应用。这些数据对于开发能够提供一致、可靠和有意义的诊断信息的算法非常宝贵,这些信息最终可用于世界各地个人疾病状况的早期诊断。
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来源期刊
Progress in Quantum Electronics
Progress in Quantum Electronics 工程技术-工程:电子与电气
CiteScore
18.50
自引率
0.00%
发文量
23
审稿时长
150 days
期刊介绍: Progress in Quantum Electronics, established in 1969, is an esteemed international review journal dedicated to sharing cutting-edge topics in quantum electronics and its applications. The journal disseminates papers covering theoretical and experimental aspects of contemporary research, including advances in physics, technology, and engineering relevant to quantum electronics. It also encourages interdisciplinary research, welcoming papers that contribute new knowledge in areas such as bio and nano-related work.
期刊最新文献
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