ASSESSMENT OF THE HEALTH STATUS IN THE MASSA LOMBARDA COHORT: A PRELIMINARY DESCRIPTION OF THE PROGRAM EVALUATING CARDIO-CEREBRO-VASCULAR DISEASE RISK FACTORS AND QUALITY OF LIFE IN AN ELDERLY POPULATION
S. NASCETTI , S. LINARELLO , M. ESCURTI , GRANDI , M. GADDONI , G. NOERA , A. GADDI
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massa lombarda队列健康状况评估:对老年人群心脑血管疾病危险因素和生活质量评估项目的初步描述
Massa Lombarda项目(MLP)是欧洲多中心项目的第一步,由博洛尼亚大学健康研究与发展学术分支机构推动和协调,旨在管理普通人群的先进卫生研究。即时个体定义(IID)研究是通过一种称为心肌灌注评分系统(MPS)的新诊断技术研究冠心病(CHD)的危险因素(RF)和早期诊断的项目的第一阶段。本研究包括对马萨隆巴达(拉文纳)成年人口(25岁以上)进行纵向观察流行病学调查,并进行社会和生物学参数调查。作为欧洲老龄人口健康状况研究的一部分,对人口中的老年人(1000名75岁以上的受试者)进行了更复杂的分析,目的是揭示影响健康老龄化的决定因素,并确定它们对死亡率、心血管和呼吸系统发病率、残疾和生活质量下降的影响。实验室分析旨在确定以下因素:(i)与促炎性和抗炎性细胞因子编码基因相关的遗传标记。(ii)氧化应激相关分子,炎症相关基因,以及更多参与脆性的一般基因(iii) (ApoE)。评估与非遗传因素的相互作用程度,如外周血中可测量的免疫标记物,氧化应激反应标记物,代谢参数的评估。此外,对老年人的饮食习惯、体力活动、自理能力、认知能力、运动协调能力、感知压力和社会关系进行问卷调查。
期刊介绍:
Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published.
Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.