BEHAVIOR IN DEGENERATIVE DEMENTIAS: MOOD DISORDERS, PSYCHOTIC SYMPTOMS AND PREDICTIVE VALUE OF NEUROPSYCHOLOGICAL DEFICITS

IF 3.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Archives of gerontology and geriatrics Pub Date : 2004-01-01 DOI:10.1016/j.archger.2004.04.047
M.C. SILVERI , B.L. SALVIGNI , C. JENNER , P. COLAMONICO
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退行性痴呆的行为:情绪障碍、精神病症状和神经心理缺陷的预测价值
本文采用不同的诊断手段对额颞叶痴呆(FTD)和阿尔茨海默病(AD)患者的情绪障碍(MD)和精神病症状(PS)进行了研究。这些是:主观量表(调查精神评估时间表子集:SPAS),客观量表(神经精神量表子集:NPI)和投射任务(Wartegg完成任务:WCT)。与SPAS相比,NPI普遍倾向于高估症状的存在,但在两个痴呆组中,症状的分布和严重程度相当均匀,独立于诊断量表。与量表的差异,WCT显示FTD比AD更严重的损害。回归分析选择的神经心理学模型只能预测FTD中的行为障碍,特别是计划缺陷可以预测PS。这些数据证实了额叶区域损伤构成退行性脑疾病中PS的神经生物学基础的假设。此外,他们认为,在大多数FTD中,行为障碍和认知缺陷应被认为是神经损伤的直接表现。
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来源期刊
CiteScore
7.30
自引率
5.00%
发文量
198
审稿时长
16 days
期刊介绍: Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.
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