BLOOD PRESSURE VARIABILITY AND COGNITIVE FUNCTION IN OLDER HYPERTENSIVES

IF 3.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Archives of gerontology and geriatrics Pub Date : 2004-01-01 DOI:10.1016/j.archger.2004.04.011
P. CICCONETTI, M. COSTARELIA, A. MOISÈ, V. CIOTTI, L. TAFARO, G. MONTEFORTE, G. PICCIRILLO, M. CACCIAFESTA
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老年高血压患者的血压变异性和认知功能
一些研究表明,脑血管器官损伤不仅与平均血压(BP)水平有关,还与血压变异性有关。本研究的目的是探讨老年高血压患者24小时血压变异性与认知功能之间的关系。40例未接受过治疗的老年高血压患者接受24小时动态血压监测(ABPM),并根据收缩压(SBP)变异性细分为两组:23例收缩压变异性较高(> PV), 17例收缩压变异性较低(< PV),定义为平均24小时收缩压值的标准差(SD)和变异系数(CV)。他们通过迷你精神状态检查(MMSE)进行认知评估,并记录脑事件相关电位(erp)。当患者受到频繁和罕见的声刺激时,erp记录神经元的电活动,并且必须识别和计数罕见的(目标)刺激。两组24小时收缩压变异性有统计学差异,MMSE评分、N2和P300 ERP潜伏期无统计学差异,提示两组认知能力无统计学差异。我们的研究结果表明,老年高血压患者的认知功能与24小时收缩压变异性无关。
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来源期刊
CiteScore
7.30
自引率
5.00%
发文量
198
审稿时长
16 days
期刊介绍: Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.
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