Constructing linkage maps with achiasmatic gametogenesis.

Ji-Xiang Wu, Jun Zhu, Johnie N Jenkins, Jack C McCarty
{"title":"Constructing linkage maps with achiasmatic gametogenesis.","authors":"Ji-Xiang Wu,&nbsp;Jun Zhu,&nbsp;Johnie N Jenkins,&nbsp;Jack C McCarty","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Maximum likelihood (ML) approach is used for estimating recombination frequency based on the achiasmatic model and the corresponding software package is developed for constructing linkage maps for achiasmatic organisms (F2 populations). The detection of sex-linked markers is done through a chi-square test. Monte Carlo simulations were conducted for comparing estimation of recombination frequency and mapping powers between these two genetic models (chiasmatic and achiasmatic models) when the achiasmata occurs. Simulation results showed that the achiasmatic model could provide unbiased estimations, while the chiasmatic model (without correction) gave under-estimates. The powers of grouping and ordering by the achiasmatic model were greater than those by the chiasmatic model (without correction) for all cases. ML approach based on the achiasmatic model can be used without correcting the data to obtain desirable linkage map powers in achiasmatic organisms.</p>","PeriodicalId":23770,"journal":{"name":"Yi chuan xue bao = Acta genetica Sinica","volume":"32 6","pages":"608-15"},"PeriodicalIF":0.0000,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Yi chuan xue bao = Acta genetica Sinica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Maximum likelihood (ML) approach is used for estimating recombination frequency based on the achiasmatic model and the corresponding software package is developed for constructing linkage maps for achiasmatic organisms (F2 populations). The detection of sex-linked markers is done through a chi-square test. Monte Carlo simulations were conducted for comparing estimation of recombination frequency and mapping powers between these two genetic models (chiasmatic and achiasmatic models) when the achiasmata occurs. Simulation results showed that the achiasmatic model could provide unbiased estimations, while the chiasmatic model (without correction) gave under-estimates. The powers of grouping and ordering by the achiasmatic model were greater than those by the chiasmatic model (without correction) for all cases. ML approach based on the achiasmatic model can be used without correcting the data to obtain desirable linkage map powers in achiasmatic organisms.

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
构建非合配子发生的连锁图谱。
利用最大似然(ML)方法估计了非交叉模型的重组频率,并开发了相应的软件包,用于构建非交叉生物(F2群体)的连锁图谱。性别连锁标记的检测是通过卡方检验完成的。通过蒙特卡罗模拟,比较了两种遗传模型(交叉模型和非交叉模型)在发生非交叉时的重组频率和作图能力的估计。仿真结果表明,交叉模型可以提供无偏估计,而交叉模型(未经校正)给出的估计较低。在所有情况下,非交叉模型的分组和排序能力均大于交叉模型(未经校正)。基于非交叉模型的机器学习方法可以在不校正数据的情况下使用,以获得理想的非交叉生物体的连锁图谱功率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
[Influence of B mating-type factor on recovery of nuclear types from dikaryons in Lentinula edodes]. [Expression and immunization testing of fusion protein of Newcastle disease virus in leaf tissue of transgenic rice]. Nuclear matrices and matrix attachment regions from Green alga: Dunaliella salina. [Molecular basic of interaction between disease resistance gene and avirulence gene]. [Progress in the study on diacylgycerol acyltransferase (DGAT)-related genes].
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1