[Meconium-stained amniotic fluid and intra-amniotic infection].

Pi-Xiang Pi, Fu-Fan Zhu, Jian Huang
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Abstract

Objective: To explore the relationship between meconium-stained amniotic fluid and Fifty-six women of cesarean section with intact membrane and intra-amniotic infection.

Methods: without parturient were divided into 3 groups according to the property of amniotic fluid (no meconium, I to approximately II degree meconium stainedness, and III degree mecomium stainedness). The content of interleukin-6 in amniotic fluid was measured with ELISA. The infiltration of inflammatory cells in the placenta and its membrane was determined by the pathological diagnosis. The neonatal Apgar score and puerperial infection after the surgery were analyzed.

Results: There were no significant differences in the content of IL-6 in amniotic fluid and in the infiltration of inflammatory cells among the 3 groups. But the rate of neonatal asphyxia in the meconium-stained cases was significantly higher than that without meconium.

Conclusion: Meconium-stained amniotic fluid is a marker of fetal distress, but it is not related to intra-amniotic infection.

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羊水粪染及羊膜内感染。
目的:探讨羊水粪染与56例膜完好剖宫产及羊膜内感染的关系。方法:根据羊水性质将未分娩孕妇分为3组(无胎粪、1 ~约2度胎粪染色、3度胎粪染色)。采用ELISA法测定羊水中白细胞介素-6的含量。通过病理诊断确定炎症细胞在胎盘及其膜中的浸润情况。分析术后新生儿Apgar评分及产褥感染情况。结果:三组大鼠羊水IL-6含量及炎症细胞浸润量差异无统计学意义。但粪染组新生儿窒息率明显高于未粪染组。结论:羊水粪染是胎儿窘迫的标志,但与羊膜内感染无关。
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