Risk of low birth weight near EUROHAZCON hazardous waste landfill sites in England.

Oliver W C Morgan, Martine Vrijheid, Helen Dolk
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引用次数: 18

Abstract

Few studies have investigated the occurrence of both low birth weight (LBW) and congenital anomalies in populations living near hazardous waste landfill sites. The authors investigated the risk of LBW near 10 English hazardous waste landfill sites included in a previous European study, which reported an increased risk of congenital anomalies. Odds ratios, adjusted for sex, deprivation, year of birth, and study area (pooled ORs), were estimated for LBW (< 2500 gm) within 0-3 km compared with 3-7 km zones around the landfill sites. The authors found a small and not statistically significant increase in risk of LBW (OR = 1.03, 95% confidence interval = 0.98-1.08) within 3 km of hazardous waste landfill sites. Their findings suggest that previously reported results for congenital anomalies should not be extrapolated to a wider range of pregnancy outcomes but should be evaluated separately for each.

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英国EUROHAZCON危险废物填埋场附近的低出生体重风险。
很少有研究调查生活在危险废物填埋场附近的人群中低出生体重(LBW)和先天性异常的发生情况。作者调查了英国10个危险垃圾填埋场附近的LBW风险,这些垃圾填埋场包括在先前的欧洲研究中,该研究报告了先天性异常的风险增加。在对性别、贫困、出生年份和研究区域(合并ORs)进行调整后,与垃圾填埋场周围3-7公里区域相比,估计了0-3公里区域内体重(< 2500克)的比值比。作者发现,在危险废物填埋场3公里范围内,LBW的风险略有增加,但没有统计学意义(OR = 1.03, 95%置信区间= 0.98-1.08)。他们的研究结果表明,先前报道的先天性异常的结果不应推断到更广泛的妊娠结局,而应分别对每种结果进行评估。
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