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Evaluation of residential exposure to intermediate frequency magnetic fields. 中频磁场对居民暴露的评价。
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602955
Yoshika Kurokawa, Hiroshi Nitta, Michinori Kabuto

The authors measured the exposure to intermediate-frequency (IF: 10 kHz to 30 MHz) electromagnetic fields (EMF) in residential environments. They developed a system to acquire and record waveforms of IF magnetic fields (MFs) and set 5 nanotesla (nT) for the trigger level of acquisition. They operated the system near power lines, railroads, and electrical appliances as possible sources of IF-MFs. Most of the maximum values of magnetic flux density and the time derivative for each wave were below the upper limit of the measurable range of our system (i.e., 53 nT and 10 T/s); these values were much lower than the minimum amplitudes that can theoretically induce heating or membrane excitation within biological systems. Moreover, the amplitudes of the IF-MFs were not related to those of extremely low frequency (ELF) MF measured simultaneously, indicating that IF-MFs do not underlie the associations, observed in several epidemiological studies, between residential exposure to ELF-EMF and childhood cancer.

作者测量了居住环境中频(中频:10千赫至30兆赫)电磁场(EMF)的暴露情况。他们开发了一个系统来获取和记录中频磁场(MFs)的波形,并设置了5纳米特斯拉(nT)作为触发采集的电平。他们在电力线、铁路和电器附近操作这个系统,因为它们可能是中频-中频的来源。磁通密度最大值和每波时间导数最大值大多低于系统可测范围的上限(即53 nT和10 T/s);这些值远远低于理论上可以在生物系统中引起加热或膜激发的最小振幅。此外,if -MF的振幅与同时测量的极低频(ELF) MF的振幅无关,这表明if -MF并不是几项流行病学研究中观察到的住宅暴露于ELF- emf与儿童癌症之间关联的基础。
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引用次数: 6
What constitutes good science in environmental and occupational health? 在环境和职业健康方面,什么是好的科学?
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602946
Tee L Guidotti
In the last issue, I addressed the role of beliefs and suppositions in (mostly) environmental health sciences. In this issue, I explore what constitutes good science in general and in the sciences of environmental and occupational health. I do this in preparation for a major change in the editorial philosophy of this journal and as guidance for future submissions. This journal is now being taken in a new editorial direction. Archives of Environmental Health will change with the next issue. The visible manifestation of this change will be a change in name to Archives of Environmental & Occupational Health, which is intended to signal a transition in editorial management and philosophy. It is also intended to return occupational health to a position of prominence in the journal. Occupational health was the original emphasis of this journal when it was founded in the 1940s. However, the changes go deeper than the name. The peer-review process has been strengthened and the standards for scientific evaluation will return to a world standard and reflect the historical tradition of this venerable journal. The next issue will mark a transition to a new and, one hopes, increasingly valuable publication. Before making this transition, however, it i s useful to reflect on the editorial board’s expectations. What constitutes good science in environmental and occupational health? The short answer is the same qualities that make for good science in general. However, how these qualities are manifest depends on the subject matter, how readily experimental or quasi-experimental design may be imposed, and the tools available for investigation. Environmental and occupational health consists of (or, more correctly, i s artificially divided into) many subfields, including environmental epidemiology, exposure assessment, occupational epidemiology, occupational hygiene, toxicology, environmental genetics and toxicogenomics, ecotoxicology, ergonomics, demographic studies of the workforce and critical industries, environmental justice studies, environmental health policy, occupational health policy, immunology applied to issues relevant to this field, physiology, studies of psychogenic stress, ecosystem and human health, risk science (which is itself a cluster of disciplines), and all the various disciplines and subdisciplines involved in monitoring and understanding media quality. Do these fields, and others not named here, some of which have no name, have anything in common that would lead us to formulate criteria for recognizing good science? It is probably easier to recognize “junk science” than to establish criteria for good science. The reason is that good science is open-minded and good and creative scientists entertain any number of ideas that they later discard or disprove. A habit of mind of excellent scientists seems to be to consider numerous ideas, some of them wildly implausible, before settling on the ones that pan out. At the same time, excellent scientis
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引用次数: 5
Increased risks of term low-birth-weight infants in a petrochemical industrial city with high air pollution levels. 空气污染程度高的石化工业城市足月低出生体重婴儿风险增加。
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602951
Chih-Ming Lin, Chung-Yi Li, I-Fang Mao

This study investigated the influence of petrochemical air pollution on birth weight. Birth data on 92,288 singleton infants with gestational periods of 37-44 wk born in a petrochemical industrial city (Kaohsiung, n = 31,530) with severe pollution or a nonpetrochemical industrial city (Taipei, n = 60,758) in Taiwan between 1995 and 1997 were included in this analysis. Air pollutant concentration derived from routinely monitored data showed significantly higher concentrations of SO2, O3, and PM10 in Kaohsiung. Infants with low birth weight (LBW) were significantly more prevalent in Kaohsiung (2.4%) than in Taipei (2.1%). Multivariable logistic regression analysis with adjustment for gestation age, gender, birth order, season of birth, maternal age, and maternal education further suggested that LBW risk in Kaohsiung was 13% higher than that in Taipei (odds ratio [OR] = 1.13, 95%, confidence interval [CI] = 1.03-1.24).

本研究探讨了石化空气污染对新生儿出生体重的影响。本研究纳入1995年至1997年间在台湾污染严重的石化工业城市(高雄,n = 31,530)或非石化工业城市(台北,n = 60,758)出生的92,288名37-44周单胎婴儿的出生资料。从日常监测数据得出的空气污染物浓度显示,高雄的SO2、O3和PM10浓度明显较高。低出生体重儿在高雄(2.4%)明显高于台北(2.1%)。经胎龄、性别、出生顺序、出生季节、母亲年龄、母亲受教育程度等因素调整后的多变量logistic回归分析进一步显示,高雄市的LBW风险比台北市高13%(优势比[OR] = 1.13, 95%,置信区间[CI] = 1.03-1.24)。
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引用次数: 21
Development and reduction of hypertension and oxidative stress among detergent industry workers. 洗涤剂工业工人高血压和氧化应激的发展和减少。
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602956
Massod M A Boojar, Faranak Goodarzi, Manochehr M A Boojar

Hypertension status and oxidative stress parameters were assessed in 291 workers (hypertensive workers were divided into three grades, non-equivalently) at two detergent production plants, one of which included enzymes in the detergent (n=138) and another which did not (n=153), and 45 control workers in another industry three times (at the time of employment, 7 yrs later at the time of installation of a filter system, and about 3 yrs later). Malondialdehyde (MDA) was measured by high-performance liquid chromatography, antioxidant enzymes and lipid status by ultraviolet-visible spectrophotometry, trace elements by atomic absorption spectroscopy, and blood pressure using an oscilometric device. Prior to filter system installation, enzyme-exposed workers had significantly higher MDA, antioxidant enzyme activities, and prevalence of hypertension, compared with controls. The filter system reduced airborne detergent and enzyme dusts, resulting in a decreased prevalence of hypertension and a significant improvement in workers' oxidative stress indicators. Alterations in antioxidant status may result from the cumulative effect of high levels of detergent and enzyme in airborne dust in the workplace.

研究人员对两家洗涤剂生产厂的291名工人(高血压工人被分为三个不同等级)的高血压状态和氧化应激参数进行了评估,其中一家工厂的洗涤剂中含有酶(n=138),另一家工厂的洗涤剂中不含酶(n=153),并对另一个行业的45名对照工人进行了三次评估(在就业时,7年后安装过滤系统时,以及大约3年后)。用高效液相色谱法测定丙二醛(MDA),紫外可见分光光度法测定抗氧化酶和脂质状态,原子吸收光谱法测定微量元素,用示波仪测定血压。在安装过滤系统之前,与对照组相比,接触酶的工人有明显更高的MDA、抗氧化酶活性和高血压患病率。过滤系统减少了空气中的洗涤剂和酶粉尘,从而降低了高血压的患病率,并显著改善了工人的氧化应激指标。抗氧化状态的改变可能是由于工作场所空气中粉尘中高浓度洗涤剂和酶的累积效应造成的。
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引用次数: 3
Determination of environmental exposure to asbestos (tremolite) and mesothelioma risks in the southeastern region of Turkey. 土耳其东南部地区石棉(透闪石)环境暴露和间皮瘤风险的测定。
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602950
Abdurrahman Senyigit, Abdurrahman Dalgic, Orhan Kavak, Abdullah Cetin Tanrikulu

In this study, the authors examined the concentrations and mineralogical analyses of asbestos, and investigated mesothelioma risk in southeastern Anatolia, Turkey. They used a gravimetric dust sampler to collect samples from 2 villages and 2 asbestos mines (1 active). Samples were then evaluated by an X-ray diffractometer and an electron microscope. The authors found high concentrations of asbestos in an active mine (4.9 fibers[f]/cm3) and at a house that was plastered with asbestos (1.24 f/cm3) and had a very active population. They found a low concentration (0.0042 f/cm3) in indoor measurements taken in Armutova village, and an even lower concentration (0.000081 f/cm3) in the inactive mine environment. Outdoor measurements included a low concentration of 0.007 f/cm3 in the village environment, and a high concentration of 1.17 f/cm3 on the mine road during the passing of a sheep herd. The people in the region are continuously exposed to asbestos during normal activities. This cumulative exposure to asbestos carries sufficient risks for mesothelioma development.

在这项研究中,作者检查了石棉的浓度和矿物学分析,并调查了土耳其安纳托利亚东南部的间皮瘤风险。他们使用重量粉尘采样器收集了2个村庄和2个石棉矿(1个活跃)的样本。然后用x射线衍射仪和电子显微镜对样品进行评估。作者在一个活跃的矿井中发现了高浓度的石棉(4.9纤维[f]/cm3),在一个涂有石棉的房子里发现了高浓度的石棉(1.24纤维/cm3),并且人口非常活跃。他们在Armutova村的室内测量中发现了低浓度(0.0042 f/cm3),在不活跃的矿井环境中发现了更低的浓度(0.000081 f/cm3)。室外测量包括村庄环境中的低浓度为0.007 f/cm3,而在羊群经过的矿山道路上的高浓度为1.17 f/cm3。该地区的居民在日常活动中持续接触石棉。这种累积的石棉暴露有足够的间皮瘤发展的风险。
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引用次数: 19
Determination of urinary trace elements (arsenic, copper, cadmium, manganese, lead, zinc, selenium) in patients with Blackfoot disease. 黑足病患者尿液微量元素(砷、铜、镉、锰、铅、锌、硒)的测定。
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602954
Jin-Lian Tsai, Pin-Hua Horng, Tzung-Jeng Hwang, John W Hsu, Ching-Jyi Horng

To determine the relationship of arsenic, copper, cadmium, manganese, lead, zinc and selenium to Blackfoot disease (BFD, a peripheral vascular disorder endemic to areas of Taiwan, which has been linked to arsenic in drinking water) the authors measured the amount of these substances in urine from BFD patients, using atomic absorption spectrometry. Results indicate significantly higher amounts of urinary arsenic, copper, cadmium, manganese, and lead for BFD patients than for normal controls, also significantly lower urinary zinc and selenium.

为了确定砷、铜、镉、锰、铅、锌和硒与黑足病(BFD,台湾地区特有的一种周围血管疾病,与饮用水中的砷有关)的关系,作者使用原子吸收光谱法测量了BFD患者尿液中这些物质的含量。结果表明,与正常对照组相比,BFD患者尿中砷、铜、镉、锰和铅的含量明显较高,尿中锌和硒的含量也明显较低。
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引用次数: 11
Medical assessment of the health effects of short leisure trips. 短期休闲旅行对健康影响的医学评估。
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602958
Masahiro Toda, Hiroaki Makino, Hidetoshi Kobayashi, Shingo Nagasawa, Kazuyuki Kitamura, Kanehisa Morimoto

Using responses to questionnaires and results of saliva samples from 40 women, the authors assessed the effects on health of participation in a short leisure trip (2 nights, 3 d) to Kyushu Island in Japan. They addressed transportation, sightseeing, and group activities during the tour, which might differ from participants' usual activities. Levels of the salivary endocrinological stress markers cortisol and chromogranin A (CgA) were determined by enzyme-linked immunosorbent assay (ELISA). In each of the groups with characteristics considered healthy and related to lifestyle, patterns of behavior, perceived stressors, and stress reactions, a decrease in the cortisol levels and an increase in the CgA levels were apparent during the tour. The baseline for stress hormone changes was the levels on awakening on Day 1 (i.e., immediately before the tour). These findings suggest that even short periods of travel can bring about a reduction in di-stress and acquisition of eu-stress, experienced as feeling uplifted or fulfilled.

通过对40名女性的问卷和唾液样本的回答,作者评估了参加日本九州岛的短期休闲旅行(2晚,3天)对健康的影响。他们讨论了旅行期间的交通、观光和团体活动,这些活动可能与参与者通常的活动不同。采用酶联免疫吸附试验(ELISA)测定各组大鼠唾液内分泌应激标志物皮质醇和嗜铬粒蛋白A (CgA)水平。在每一组被认为健康且与生活方式、行为模式、感知到的压力源和压力反应相关的特征中,皮质醇水平的下降和CgA水平的增加在旅行期间是明显的。应激激素变化的基线是第一天醒来时的水平(即旅行前)。这些发现表明,即使是短时间的旅行也能减少减压和获得压力,体验到振奋或满足的感觉。
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引用次数: 23
Effectiveness of clean indoor air ordinances in controlling environmental tobacco smoke in restaurants. 洁净室内空气条例在控制食肆环境烟草烟雾方面的成效。
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602953
Farhang Akbar-Khanzadeh, Sheryl Milz, April Ames, Sara Spino, Christopher Tex

Clean indoor air (CIA) ordinances in Toledo, Ohio, and Bowling Green, Ohio, regulate smoking in restaurants to protect patrons and employees. Yet complete protection is questionable because the ordinances allow for smoking in certain dining sections. Two restaurants were studied in each city, one smoking and one nonsmoking. Levels of contaminants related to environmental tobacco smoke (ETS)--determined by personal and area air monitoring-in the nonsmoking restaurants were comparable to levels in a control environment. However, levels of ETS-related contaminants in the smoking restaurants, including designated nonsmoking sections, were significantly higher than levels in the control environment. ETS-related contamination of the nonsmoking sections in the smoking restaurants is attributable to direct openings between the smoking and nonsmoking sections. Reasonable protection of employees and patrons against ETS-related contaminants requires strict enforcement of CIA ordinances. Full protection is achievable only with 100% smoke-free policies.

俄亥俄州托莱多市和俄亥俄州鲍灵格林市的清洁室内空气条例规定在餐馆吸烟,以保护顾客和雇员。然而,完全的保护是值得怀疑的,因为条例允许在某些用餐区域吸烟。每个城市研究了两家餐馆,一家吸烟,一家不吸烟。与环境烟草烟雾(ETS)相关的污染物水平——由个人和区域空气监测确定——在禁烟餐厅中与对照环境中的水平相当。然而,在吸烟餐厅,包括指定的非吸烟区,与碳排放体系相关的污染物水平明显高于对照环境。吸烟餐厅非吸烟区的污染主要是由于吸烟区和非吸烟区之间的直接开口造成的。合理保护雇员和赞助人免受ets相关污染物的侵害需要严格执行中央情报局的条例。只有100%无烟政策才能实现全面保护。
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引用次数: 10
Relationship between health status and psychological distress among the inhabitants in a methylmercury-polluted area in Japan. 日本甲基汞污染地区居民健康状况与心理困扰的关系
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602959
Kayo Ushijima, Yoshihiro Miyake, Takao Kitano, Masahiro Shono, Makoto Futatsuka

This study examined the relationship between health parameters and psychological distress among inhabitants of methylmercury-polluted areas in Japan. The subjects were 133 inhabitants over the age of 40 yr living in two methylmercury-polluted villages. Information on demographic factors, health status, and mental health was obtained using questionnaires, including the General Health Questionnaire (GHQ). The proportional odds model was used to estimate the adjusted odds ratios of factors associated with a higher GHQ score after adjustment for age, gender, and district. Very poor self-rated health status, a high number (5+) of subjective symptoms, having monthly outpatient visits and medical house calls, and receiving compensation for methylmercury poisoning were significantly associated with psychological distress. Poor physical condition may lead to the development of psychological distress.

本研究调查了日本甲基汞污染地区居民的健康参数与心理困扰之间的关系。研究对象是居住在两个甲基汞污染村庄的133名40岁以上的居民。通过问卷,包括一般健康问卷(GHQ),获得了有关人口因素、健康状况和心理健康的信息。比例优势模型用于估计调整年龄、性别和地区后与较高GHQ评分相关因素的调整优势比。自我评价的健康状况极差、主观症状较多(5个以上)、每月门诊和出诊以及接受甲基汞中毒补偿与心理困扰显著相关。身体状况不佳可能导致心理困扰的发展。
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引用次数: 9
Exposure of a Cree population living near mine tailings in northern Quebec (Canada) to metals and metalloids. 居住在加拿大魁北克北部矿山尾矿附近的克里族人对金属和类金属的暴露。
Pub Date : 2004-12-01 DOI: 10.1080/00039890409602960
Dominique Bussières, Pierre Ayotte, Patrick Levallois, Eric Dewailly, Evert Nieboer, Suzanne Gingras, Suzanne Côté

The authors investigated the effect of residues from copper- and gold-mining on the Cree population of Oujé-Bougoumou, located 560 km north of Quebec City, Canada. Subjects (225) from Oujé-Bougoumou and a control population (100) completed a questionnaire on lifestyle and dietary habits and provided blood and urine samples for analysis. Geometric means of arsenic, lead, cadmium, and copper concentrations were not significantly different for subjects or controls 15 yr and older or children (8-14 yr old). However, blood zinc was higher and selenium was lower in Oujé-Bougoumou samples. Mean blood lead level was higher in children from Oujé-Bougoumou, but lower in adults aged 40 yr and older. For adults (15 yr and older) blood lead level increased with age and was higher in men, those who hunted, and consumed wild meat (R2 = 0.43). Blood cadmium increased with age and smoking (R2 = 0.61). No influence of mine residues was observed among residents of Oujé-Bougoumou, but lifestyle exposure associations were noted for both communities.

作者调查了铜矿和金矿开采残留物对位于加拿大魁北克市以北560公里的ouj -布古牟的克里族人口的影响。来自ouj -布古mou的225名受试者和对照人群(100名)完成了关于生活方式和饮食习惯的问卷调查,并提供了血液和尿液样本供分析。砷、铅、镉和铜浓度的几何平均值在15岁及以上的受试者或对照者或儿童(8-14岁)中没有显著差异。乌伊姆-布古牟样品血锌含量较高,硒含量较低。ouj郁闷-布古牟地区儿童的平均血铅水平较高,但40岁及以上成年人的平均血铅水平较低。对于成年人(15岁及以上),血铅水平随着年龄的增长而增加,男性、狩猎和食用野生肉类的人血铅水平更高(R2 = 0.43)。血镉随年龄和吸烟增加而增加(R2 = 0.61)。在ouj -布古牟居民中没有观察到地雷残留物的影响,但两个社区都注意到生活方式暴露的关联。
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引用次数: 14
期刊
Archives of environmental health
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