Bone mineral content of the mandible and spine in ovariectomized rats with estrogen deficiency.

Abstract

The aim of this study was to assess the bone mineral content of the mandible and spine in rats with estrogen deficiency after ovariectomy. Female rats were divided into the following groups: CL--control, SH--sham-operated, OV--after ovariectomy, OVH--after ovariectomy receiving 17beta-estradiol in three different doses (1.25, 12.5, 125 microg) during seven weeks. After the experiment densitometric examinations of the mandible and spine were made using DEXA method and there was measured bone mineral content (BMC). The results of the examination indicate that estrogen deficiency after ovariectomy leads to decreasing of BMC index of the examined bones, and densitometric examinations allow to carefully evaluate changes in the mineral part of the examined bones.