Sleep Apnea and Skin.

IF 1.5 Q4 CLINICAL NEUROLOGY Current Sleep Medicine Reports Pub Date : 2020-09-01 Epub Date: 2020-08-25 DOI:10.1007/s40675-020-00179-7

Vinaya Soundararajan, Jennifer Lor, Anna B Fishbein

{"title":"Sleep Apnea and Skin.","authors":"Vinaya Soundararajan, Jennifer Lor, Anna B Fishbein","doi":"10.1007/s40675-020-00179-7","DOIUrl":null,"url":null,"abstract":"Purpose of the review: Skin disease is associated with obstructive sleep apnea (OSA) both epidemiologically and mechanistically. In this review we highlight conditions which have a well-established link to obstructive sleep apnea, such as psoriasis and atopic dermatitis.Recent findings: We describe putative mechanistic links between OSA and skin disease involving inflammatory pathways, obesity, mechanical upper airways obstruction, and hypoxia. In the context of these mechanisms we describe specific skin conditions, and other conditions which are associated with both skin manifestations (including hair/nail findings) and OSA. The risks/ benefits of CPAP in the context of skin disease are also reviewed.Summary: We conclude that further research is needed to understand the mechanisms behind the associations between OSA and skin disease. Given the frequent co-occurrence of OSA and skin conditions, there would be great benefit for OSA clinical trials to consider improvement in skin disease as an outcome measure.","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"6 3","pages":"94-100"},"PeriodicalIF":1.5000,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40675-020-00179-7","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Sleep Medicine Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40675-020-00179-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/8/25 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 3

Abstract

Purpose of the review: Skin disease is associated with obstructive sleep apnea (OSA) both epidemiologically and mechanistically. In this review we highlight conditions which have a well-established link to obstructive sleep apnea, such as psoriasis and atopic dermatitis.

Recent findings: We describe putative mechanistic links between OSA and skin disease involving inflammatory pathways, obesity, mechanical upper airways obstruction, and hypoxia. In the context of these mechanisms we describe specific skin conditions, and other conditions which are associated with both skin manifestations (including hair/nail findings) and OSA. The risks/ benefits of CPAP in the context of skin disease are also reviewed.

Summary: We conclude that further research is needed to understand the mechanisms behind the associations between OSA and skin disease. Given the frequent co-occurrence of OSA and skin conditions, there would be great benefit for OSA clinical trials to consider improvement in skin disease as an outcome measure.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

睡眠呼吸暂停和皮肤。

综述的目的:皮肤病与阻塞性睡眠呼吸暂停(OSA)在流行病学和机制上都有关联。在这篇综述中，我们强调了与阻塞性睡眠呼吸暂停有明确联系的疾病，如牛皮癣和特应性皮炎。最近的研究发现:我们描述了OSA与皮肤疾病之间可能的机制联系，包括炎症途径、肥胖、机械性上呼吸道阻塞和缺氧。在这些机制的背景下，我们描述了特定的皮肤状况，以及与皮肤表现(包括头发/指甲的发现)和OSA相关的其他状况。本文还回顾了CPAP治疗皮肤病的风险/益处。总结:我们的结论是，需要进一步的研究来了解阻塞性睡眠呼吸暂停和皮肤疾病之间关联的机制。考虑到OSA与皮肤病的频繁共存，将皮肤病的改善作为OSA临床试验的结果衡量标准将大有裨益。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Current Sleep Medicine Reports Medicine-Pulmonary and Respiratory Medicine

CiteScore

2.50

自引率

5.60%

发文量

期刊介绍： Current Sleep Medicine Reports aims to review the most important, recently published articles in the field of sleep medicine. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of sleep conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as insomnia, narcolepsy, sleep apnea, circadian rhythm disorders, and parasomnias. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.